发明授权
- 专利标题： AKT protein kinase inhibitors
- 专利标题（中）： AKT蛋白激酶抑制剂
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申请号： US12567258申请日： 2009-09-25
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公开(公告)号： US08680114B2公开(公告)日： 2014-03-25
- 发明人: Ian S. Mitchell , Keith L. Spencer , Peter Stengel , Yongxin Han , Nicholas C. Kallan , Mark Munson , Guy P. A. Vigers , James Blake , Anthony Piscopio , John Josey , Scott Miller , Dengming Xiao , Rui Xu , Chang Rao , Bing Wang , April L. Bernacki
- 申请人： Ian S. Mitchell , Keith L. Spencer , Peter Stengel , Yongxin Han , Nicholas C. Kallan , Mark Munson , Guy P. A. Vigers , James Blake , Anthony Piscopio , John Josey , Scott Miller , Dengming Xiao , Rui Xu , Chang Rao , Bing Wang , April L. Bernacki
- 申请人地址： US CO Boulder US CA South San Francisco
- 专利权人： Array Biopharma, Inc.,Genentech, Inc.
- 当前专利权人： Array Biopharma, Inc.,Genentech, Inc.
- 当前专利权人地址： US CO Boulder US CA South San Francisco
- 代理机构： Viksnins Harris & Padys PLLP
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; A01N43/42 ; C07D215/00
摘要：
The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
公开/授权文献
- US20100168123A1 AKT PROTEIN KINASE INHIBITORS 公开/授权日：2010-07-01
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