摘要:
The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
摘要:
The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
摘要:
Processes and reagents for inhibiting or eliminating scale formation during wet-process phosphoric acid production are provided and include adding to a wet-process phosphoric acid production stream a scale inhibiting amount of a reagent having an aliphatic or aromatic compound containing at least two hydroxy groups, and at least one amine.
摘要:
The invention provides a composition comprising lactoferrin for use in the prevention, amelioration, or treatment of diarrhea, in particular non-infectious weaning diarrhea of infants or children.
摘要:
A lever control mechanism of a drain valve of a toilet tank has a lever assembly assembled in the wall of the toilet tank and a lever linked to the revolving shaft of the lever assembly. The lever assembly is connected to a deviator, which is disposed with a drive arm; the drive arm is connected to the revolving shaft. The deviator is disposed with a joint portion and at least a leading hole to limit the lever revolving vertically. One end of the lever is run through the leading hole to rotationally connect to the joint portion; the drive arm is revolved by the driving of the revolving shaft to drive the lever revolved in the fan shaped vertical surface limited formed by the joint portion and the leading hole.
摘要:
A memory macro includes a tracking circuit and a plurality of memory cells. The tracking circuit has tracking transistors configured to receive a tracking voltage value. Each memory cell of the plurality of memory cells has memory transistors configured to receive a cell voltage value different from the tracking voltage value. The tracking circuit is configured to generate a tracking signal based on which a reading signal of a memory cell of the plurality of memory cells is generated.
摘要:
A two level cross-correlation based system for watermarking continuous digital media at the system application level. It is a post-compression process for watermarking where no a priori knowledge of the underlying compression algorithm is required. Per each compressed media frame, a current unique digital signature is generated based on the data from the current compressed frame plus the digital signature that has been previously generated. The signature thus generated is then used in conjunction with the next compressed frame to generate the next unique digital signature. All digital signatures are correlated according to the above process until a “reset” signal is issued. A new chain of correlated digital signatures is produced by the system with a predetermined initial signature.
摘要:
The invention relates to compounds of formula (I): where A is an optionally substituted heteroaryl, useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.
摘要:
A preparation method of rosuvastatin calcium (Formula 1), which can be used for the production of medicament lowering the levels of LDL-cholesterol and triglycerides in vivo, is provided. Such preparation method is suitable for industrial production. Furthermore, the intermediate crystallines used in the preparation method are provided.
摘要:
A Static Random Access Memory (SRAM) includes at least two memory cells sharing a read bit line (RBL) and a write bit line (WBL). Each memory cell is coupled to a respective read word line (RWL) and a respective write word line (WWL). A write tracking control circuit is coupled to the memory cells for determining a write time of the memory cells. The write tracking control circuit is capable of receiving an input voltage and providing an output voltage. The respective RWL and the respective WWL of each memory cell are asserted during a write tracking operation.