发明授权
US08710077B2 Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
有权
环烷基胺取代的异喹啉和异喹啉酮衍生物
- 专利标题: Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
- 专利标题(中): 环烷基胺取代的异喹啉和异喹啉酮衍生物
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申请号: US12487503申请日: 2009-06-18
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公开(公告)号: US08710077B2公开(公告)日: 2014-04-29
- 发明人: Oliver Plettenburg , Katrin Lorenz , Jochen Goerlitzer , Matthias Löhn , Sandrine Biscarrat , Fréderic Jeannot , Olivier Duclos
- 申请人: Oliver Plettenburg , Katrin Lorenz , Jochen Goerlitzer , Matthias Löhn , Sandrine Biscarrat , Fréderic Jeannot , Olivier Duclos
- 申请人地址: FR Paris
- 专利权人: Sanofi
- 当前专利权人: Sanofi
- 当前专利权人地址: FR Paris
- 代理机构: Scully, Scott, Murphy & Presser, P.C.
- 优先权: EP06026897 20061227
- 主分类号: A61K31/47
- IPC分类号: A61K31/47 ; C07D217/00
摘要:
The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
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