发明授权
- 专利标题: Modulators of ATP-Binding Cassette transporters
- 专利标题(中): ATP结合盒转运蛋白的调节剂
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申请号: US13492164申请日: 2012-06-08
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公开(公告)号: US08802700B2公开(公告)日: 2014-08-12
- 发明人: Urvi Sheth , Lev T. D. Fanning , Mehdi Numa , Hayley Binch , Dennis James Hurley , Jinglan Zhou , Sara S. Hadida Ruah , Anna R. Hazlewood , Alina Silina , Rajendran Vairagoundar , Fredrick F. Van Goor , Peter Diederik Jan Grootenhuis , Martyn C. Botfield
- 申请人: Urvi Sheth , Lev T. D. Fanning , Mehdi Numa , Hayley Binch , Dennis James Hurley , Jinglan Zhou , Sara S. Hadida Ruah , Anna R. Hazlewood , Alina Silina , Rajendran Vairagoundar , Fredrick F. Van Goor , Peter Diederik Jan Grootenhuis , Martyn C. Botfield
- 申请人地址: US MA Boston
- 专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人地址: US MA Boston
- 代理机构: Honigman Miller Schwartz and Cohn LLP
- 代理商 Christopher C. Forbes; Jonathan P. O'Brien
- 主分类号: A61K31/04
- IPC分类号: A61K31/04 ; A61K31/4725 ; A61K31/4709
摘要:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
公开/授权文献
- US20120309758A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS 公开/授权日:2012-12-06
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