Invention Grant
- Patent Title: Methods of generating mature oligodendrocytes
- Patent Title (中): 产生成熟少突胶质细胞的方法
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Application No.: US12310495Application Date: 2007-08-15
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Publication No.: US08809052B2Publication Date: 2014-08-19
- Inventor: Michel Revel , Judith Chebath , Michal Izrael , Rosalia Kaufman
- Applicant: Michel Revel , Judith Chebath , Michal Izrael , Rosalia Kaufman
- Applicant Address: IL Rechovot
- Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee Address: IL Rechovot
- Agency: Polsinelli PC
- Agent Teddy C. Scott, Jr.; Ron Galant
- International Application: PCT/IL2007/001026 WO 20070815
- International Announcement: WO2008/026198 WO 20080306
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N5/00
Abstract:
A method of generating neural and glial cells is provided. The method comprising growing human stem cells under conditions which induce differentiation of said human stem cells into the neural and glial cells, said conditions comprising the presence of retinoic acid and an agent capable of down-regulating Bone Morphogenic Protein activity.
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