发明授权
US08835440B2 Cyclic pyrimidin-4-carboxamides as CCR2 receptor antagonists for treatment of inflammation, asthma and COPD
有权
循环嘧啶-4-甲酰胺作为治疗炎症，哮喘和COPD的CCR2受体拮抗剂
- 专利标题： Cyclic pyrimidin-4-carboxamides as CCR2 receptor antagonists for treatment of inflammation, asthma and COPD
- 专利标题（中）： 循环嘧啶-4-甲酰胺作为治疗炎症，哮喘和COPD的CCR2受体拮抗剂
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申请号： US13949696申请日： 2013-07-24
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公开(公告)号： US08835440B2公开(公告)日： 2014-09-16
- 发明人: Heiner Ebel , Sara Frattini , Riccardo Giovannini , Christoph Hoenke , Thomas Trieselmann , Patrick Tielmann , Stefan Scheuerer , Silke Hobbie , Frank Buettner
- 申请人： Heiner Ebel , Sara Frattini , Riccardo Giovannini , Christoph Hoenke , Thomas Trieselmann , Patrick Tielmann , Stefan Scheuerer , Silke Hobbie , Frank Buettner
- 申请人地址： DE Ingelheim am Rhein
- 专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人地址： DE Ingelheim am Rhein
- 代理商 Michael P. Morris; Edward S. Lazer
- 优先权： EP08172336 20081219; EP09160416 20090515
- 主分类号： A01N43/54
- IPC分类号： A01N43/54 ; C07D239/42 ; C07D401/04 ; C07D498/10 ; C07D403/06 ; A61K31/55 ; C07D491/052 ; C07D401/06 ; A61K31/553 ; C07D405/14 ; C07D471/10 ; C07D407/14 ; C07D417/14 ; A61K31/5377 ; A61K31/551 ; C07D471/04 ; C07D403/14 ; C07D451/02 ; C07D401/14 ; A61K31/506 ; C07D413/14
摘要：
The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.
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