发明授权
- 专利标题: Method for the biotechnological production of valuable products
- 专利标题(中): 生物技术生产有价值产品的方法
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申请号: US10521387申请日: 2003-06-21
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公开(公告)号: US08846383B2公开(公告)日: 2014-09-30
- 发明人: Reiner Luttmann , Wilfried Kappel , Toralf Gliem , Mohammad Saeed Ajam , Lars Boettcher , Bernd-Ulrich Wilhelm , Wolfgang Rietschel
- 申请人: Reiner Luttmann , Wilfried Kappel , Toralf Gliem , Mohammad Saeed Ajam , Lars Boettcher , Bernd-Ulrich Wilhelm , Wolfgang Rietschel
- 申请人地址: DE Gottingen
- 专利权人: Sartorius AG
- 当前专利权人: Sartorius AG
- 当前专利权人地址: DE Gottingen
- 代理商 Gerald E. Hespos; Michael J. Porco; Matthew T. Hespos
- 优先权: DE10237082 20020809
- 国际申请: PCT/EP03/06565 WO 20030621
- 国际公布: WO2004/018692 WO 20040304
- 主分类号: C12M1/12
- IPC分类号: C12M1/12 ; B01D61/14 ; B01D61/22 ; C12P21/00 ; C12M1/00 ; C12M1/34
摘要:
Disclosed are a method and a device for the biotechnological production of valuable products, in which a medium is fed to a bioreactor and is subjected to a fermentation process, the valuable product is gathered as a filtered permeate and/or concentrated retentate via a cross-flow filtration system that is mounted downstream thereof, and residues are once again fed to the bioreactor until being gathered as a retentate. Other materials can be fed to the bioreactor in a controlled manner in addition to the medium while the concentrated retentate and permeate can be gathered in a controlled manner. The fermentation process and the filtration process are regulated in a synchronized manner in an integrated system via a digital control unit.