发明授权
- 专利标题： Treatment of disease conditions via administration of DNA repair enzyme
- 专利标题（中）： 通过施用DNA修复酶治疗疾病状况
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申请号： US12866540申请日： 2009-02-09
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公开(公告)号： US08865160B2公开(公告)日： 2014-10-21
- 发明人: Glenn Wilson , Susan Ledoux , Mikhail Alexeyev , Inna Shokolenko , Mark N. Gillespie
- 申请人： Glenn Wilson , Susan Ledoux , Mikhail Alexeyev , Inna Shokolenko , Mark N. Gillespie
- 申请人地址： US AL Mobile
- 专利权人： University of South Alabama
- 当前专利权人： University of South Alabama
- 当前专利权人地址： US AL Mobile
- 代理机构： Lerner, David, Littenberg, Krumholz & Mentlik, LLP
- 国际申请： PCT/US2009/000889 WO 20090209
- 国际公布： WO2009/099679 WO 20090813
- 主分类号： A61K38/54
- IPC分类号： A61K38/54 ; A61P11/00 ; A61P1/00 ; C12N5/0781 ; C12N9/22 ; A61K47/48 ; C12N9/88 ; C12N9/24 ; A61K38/00
摘要：
The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various diseases and other abnormal or pathological conditions, including inflammatory bowel disease, ischemic heart disease, acute lung injury, acute respiratory distress syndrome and radiation-induced brain injury, with DNA repair enzymes that are directed to the mitochondria.
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