发明授权
US08871873B2 Biodegradable particle, vascular embolization material and method for producing biodegradable particles
有权
生物降解颗粒,血管栓塞材料及生物降解颗粒的生产方法
- 专利标题: Biodegradable particle, vascular embolization material and method for producing biodegradable particles
- 专利标题(中): 生物降解颗粒,血管栓塞材料及生物降解颗粒的生产方法
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申请号: US14008194申请日: 2012-03-29
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公开(公告)号: US08871873B2公开(公告)日: 2014-10-28
- 发明人: Masaki Fujita , Megumi Nakanishi , Yoshitake Takahashi , Yasufumi Yamamura , Kazuhiro Tanahashi
- 申请人: Masaki Fujita , Megumi Nakanishi , Yoshitake Takahashi , Yasufumi Yamamura , Kazuhiro Tanahashi
- 申请人地址: JP
- 专利权人: Toray Industries, Inc.
- 当前专利权人: Toray Industries, Inc.
- 当前专利权人地址: JP
- 代理机构: DLA Piper LLP (US)
- 优先权: JP2011-076155 20110330
- 国际申请: PCT/JP2012/058293 WO 20120329
- 国际公布: WO2012/133608 WO 20121004
- 主分类号: A61L24/04
- IPC分类号: A61L24/04 ; A61L24/00 ; C08J3/28 ; C08G63/664 ; C08G63/08 ; A61L31/06 ; A61L31/14 ; C08G65/32
摘要:
A biodegradable particle including a block copolymer produced by copolymerization of a biodegradable copolymer having a structure composed of hydroxycarboxylic acid a1, whose homopolymer produced by homopolymerization has a glass transition point of not less than 40° C., and hydroxycarboxylic acid a2, whose homopolymer produced by homopolymerization has a glass transition point of not more than −40° C.; a water-soluble polymer comprising a functional group selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group at each of both ends; and a polyvalent compound comprising 2 or more functional groups each selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group; wherein a ratio of mass of said structure composed of hydroxycarboxylic acid a2 to mass of said biodegradable copolymer is 30 to 90% by mass.
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