利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

20 条记录 (耗时 0.019 秒)

    METHOD FOR PRODUCING POLYLACTIC ACID BLOCK COPOLYMER
    3.
    发明申请
    METHOD FOR PRODUCING POLYLACTIC ACID BLOCK COPOLYMER 有权
    制备聚酸嵌段共聚物的方法

    公开(公告)号：US20130158209A1

    公开(公告)日：2013-06-20

    申请号：US13819199

    申请日：2011-06-27

    申请人： Yoshitake Takahashi ,  Takuma Naotsuka ,  Ken Sudo ,  Hiroyuki Ome

    发明人： Yoshitake Takahashi ,  Takuma Naotsuka ,  Ken Sudo ,  Hiroyuki Ome

    IPC分类号： C08G63/80

    CPC分类号： C08G63/80 ,  C08G63/06 ,  C08G63/08 ,  C08G63/823 ,  C08G63/912 ,  C08G2261/126 ,  C08L67/04 ,  C08L2205/025 ,  C08L2205/05

    摘要： A method of producing a polylactic acid block copolymer constituted of a segment(s) composed of L-lactic acid units and a segment(s) composed of D-lactic acid units, includes obtaining a mixture by mixing poly-L-lactic acid and poly-D-lactic acid one of which has a weight average molecular weight of 60,000 to 300,000 and the other of which has a weight average molecular weight of 10,000 to 50,000, the mixture having a weight average molecular weight of not less than 90,000 and a degree of stereocomplexation (Sc) satisfying: Sc=ΔHh/(ΔHl+ΔHh)×100>60 (wherein ΔHh represents the heat of fusion of stereocomplex crystals (J/g), and ΔHl represents the heat of fusion of crystals of poly-L-lactic acid alone and crystals of poly-D-lactic acid alone (J/g)); and subsequently subjecting the mixture to solid-phase polymerization at a temperature lower than the melting point of the mixture.

    摘要翻译： 由L-乳酸单元构成的链段和由D-乳酸单元构成的链段构成的聚乳酸嵌段共聚物的制造方法包括：将聚-L-乳酸和 聚D-乳酸的重均分子量为60000〜300000，另一个重均分子量为10,000〜50,000，该重均分子量不小于90,000， 立方复合度（Sc）满足：Sc = DeltaHh /（DeltaH1 +ΔHh）×100> 60（其中DeltaHh表示立体络合物晶体的熔化热（J / g），ΔH1表示聚 - 单独使用L-乳酸和单独的聚-D-乳酸晶体（J / g））; 然后在比混合物的熔点低的温度下使混合物进行固相聚合。

    BIODEGRADABLE PARTICLE, VASCULAR EMBOLIZATION MATERIAL AND METHOD FOR PRODUCING BIODEGRADABLE PARTICLES
    9.
    发明申请
    BIODEGRADABLE PARTICLE, VASCULAR EMBOLIZATION MATERIAL AND METHOD FOR PRODUCING BIODEGRADABLE PARTICLES 有权
    生物可降解颗粒，生物可降解颗粒的血管形成材料和方法

    公开(公告)号：US20140018505A1

    公开(公告)日：2014-01-16

    申请号：US14008194

    申请日：2012-03-29

    申请人： Masaki Fujita ,  Megumi Nakanishi ,  Yoshitake Takahashi ,  Yasufumi Yamamura ,  Kazuhiro Tanahashi

    发明人： Masaki Fujita ,  Megumi Nakanishi ,  Yoshitake Takahashi ,  Yasufumi Yamamura ,  Kazuhiro Tanahashi

    IPC分类号： A61L24/04 ,  A61L24/00

    CPC分类号： A61L24/046 ,  A61L24/0042 ,  A61L31/06 ,  A61L31/148 ,  A61L2430/36 ,  C08G63/08 ,  C08G63/664 ,  C08J3/28 ,  C08J2367/04 ,  C08L67/04

    摘要： A biodegradable particle including a block copolymer produced by copolymerization of a biodegradable copolymer having a structure composed of hydroxycarboxylic acid a1, whose homopolymer produced by homopolymerization has a glass transition point of not less than 40° C. and hydroxycarboxylic acid a2, whose homopolymer produced by homopolymerization has a glass transition point of not more than −40° C.; a water-soluble polymer comprising a functional group selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group at each of both ends; and a polyvalent compound comprising 2 or more functional groups each selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group; wherein a ratio of mass of said structure composed of hydroxycarboxylic acid a2 to mass of said biodegradable copolymer is 30 to 90% by mass.

    摘要翻译： 包含由具有由均聚产生的均聚物的羟基羧酸a1构成的结构的生物降解性共聚物的共聚制得的嵌段共聚物的玻璃化转变温度为40℃以上的生物降解性粒子和羟基羧酸a2，其均聚物由 均聚反应玻璃化转变温度不高于-40℃。 在两端各自包含选自羟基，氨基和羧酸基的官能团的水溶性聚合物; 和包含2个以上选自羟基，氨基和羧酸基的官能团的多价化合物; 其中由羟基羧酸a2构成的所述结构的质量与所述生物降解性共聚物的质量之比为30〜90质量％。