发明授权
- 专利标题: Processes for preparing tubulysins
- 专利标题(中): 肾上腺素的制备方法
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申请号: US13814336申请日: 2011-08-05
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公开(公告)号: US08889880B2公开(公告)日: 2014-11-18
- 发明人: Iontcho Radoslavov Vlahov , Michael Groaning , Paul Joseph Kleindl , Hari Krishna R. Santhapuram , Fei You , Kevin Yu Wang , Le-Cun Xu , Katheryn Marie Stanford , Allen Ritter , Christopher Paul Leamon
- 申请人: Iontcho Radoslavov Vlahov , Michael Groaning , Paul Joseph Kleindl , Hari Krishna R. Santhapuram , Fei You , Kevin Yu Wang , Le-Cun Xu , Katheryn Marie Stanford , Allen Ritter , Christopher Paul Leamon
- 申请人地址: US IN West Lafayette
- 专利权人: Endocyte, Inc.
- 当前专利权人: Endocyte, Inc.
- 当前专利权人地址: US IN West Lafayette
- 代理机构: Barnes & Thornburg LLP
- 国际申请: PCT/US2011/046797 WO 20110805
- 国际公布: WO2012/019123 WO 20120209
- 主分类号: A61K31/425
- IPC分类号: A61K31/425 ; C07D277/04 ; C07K5/02 ; A61K31/445 ; C07D417/12
摘要:
Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for preparing naturally occurring and non-naturally occurring tubulysins and analogs and derivatives thereof are described.
公开/授权文献
- US20130137139A1 PROCESSES FOR PREPARING TUBULYSINS 公开/授权日:2013-05-30
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