A line voltage control circuit for use with a multi-string LED drive system which provides a common line voltage for multiple LED strings that are connected to respective current sink circuits at respective junctions. An error amplifier receives the minimum junction voltage and a reference ‘desired junction voltage’ at respective inputs, and a voltage regulator outputs the line voltage in response to a voltage applied to a feedback input. A comparator toggles an output when the maximum junction voltage (Vmax) exceeds a reference limit (Vlimit). A multiplexer receives the error amplifier output and a fixed voltage at respective inputs and provides one of the signals to the regulator's feedback input in response to the comparator output. When Vmax>Vlimit, the fixed voltage is provided to the feedback input and the line voltage is reduced, thereby protecting low voltage current sinks from potentially damaging high voltages.