Invention Grant
US08906359B2 Recombinant retrovirus pseudotyped with a E2 alphavirus glycoprotein
有权
用E2甲病毒糖蛋白假型包装的重组逆转录病毒
- Patent Title: Recombinant retrovirus pseudotyped with a E2 alphavirus glycoprotein
- Patent Title (中): 用E2甲病毒糖蛋白假型包装的重组逆转录病毒
-
Application No.: US13887908Application Date: 2013-05-06
-
Publication No.: US08906359B2Publication Date: 2014-12-09
- Inventor: Pin Wang , Lili Yang , David Baltimore
- Applicant: California Institute of Technology
- Applicant Address: US CA Pasadena
- Assignee: California Institute of Technology
- Current Assignee: California Institute of Technology
- Current Assignee Address: US CA Pasadena
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A01N65/00 ; A61K48/00 ; C12N5/00
Abstract:
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.
Public/Granted literature
- US20130230554A1 TARGETED GENE DELIVERY FOR DENDRITIC CELL VACCINATION Public/Granted day:2013-09-05
Information query
