发明授权
US08980628B2 Hair follicle precursor production by co-culturing mammalian dermal papilla cells and keratinocytes
有权
通过共培养哺乳动物真皮乳头细胞和角质形成细胞产生毛囊前体
- 专利标题： Hair follicle precursor production by co-culturing mammalian dermal papilla cells and keratinocytes
- 专利标题（中）： 通过共培养哺乳动物真皮乳头细胞和角质形成细胞产生毛囊前体
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申请号： US12293402申请日： 2007-03-15
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公开(公告)号： US08980628B2公开(公告)日： 2015-03-17
- 发明人: Jizeng Qiao , Jeffrey Keeler Teumer , Erica Jean Philips
- 申请人： Jizeng Qiao , Jeffrey Keeler Teumer , Erica Jean Philips
- 申请人地址： US CA Beverly Hills
- 专利权人： Aderans Research Institute, Inc.
- 当前专利权人： Aderans Research Institute, Inc.
- 当前专利权人地址： US CA Beverly Hills
- 代理机构： Pabst Patent Group LLP
- 优先权： GBGB0605450.6 20060317
- 国际申请： PCT/US2007/006790 WO 20070315
- 国际公布： WO2007/109223 WO 20070927
- 主分类号： C12N5/02
- IPC分类号： C12N5/02 ; A61L27/38 ; C12N5/077 ; C12N5/071 ; C12N5/0775
摘要：
This invention relates to methods of producing hair folliclesin vitro, compositions for producing hair follicles in vitro, in vitro produced hair follicles, methods of providing an in vitro produced hair shaft at an interfollicular or intrafollicular site, methods of treating hair loss by providing an in vitro produced hair shaft at an interfollicular or intrafollicular site and assays for studying the effect of test agents on hair biology. The invention also provides the similar methods and products which are, or use, immature follicles (“defined herein as proto-hairs”). The invention provides a method for in vitro production of a hair follicle or a proto-hair comprising co-culturing dermal papilla cells with keratinocytes, and optionally with melanocytes.
公开/授权文献
- US20090198336A1 CELL CO-CULTURE FOR HAIR FOLLICLE PRODUCTION 公开/授权日：2009-08-06
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