Invention Grant
US08981064B2 Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
有权
抗原结合蛋白与蛋白转化酶枯草杆菌蛋白酶Kexin 9型（PCSK9）
- Patent Title: Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
- Patent Title (中): 抗原结合蛋白与蛋白转化酶枯草杆菌蛋白酶Kexin 9型（PCSK9）
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Application No.: US14459743Application Date: 2014-08-14
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Publication No.: US08981064B2Publication Date: 2015-03-17
- Inventor: Simon Mark Jackson , Bei Shan , Wenyan Shen , Chadwick Terence King , Randal Robert Ketchem , Christopher Mehlin , Teresa Arazas Carabeo
- Applicant: Amgen Inc.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Knobbe, Martens, Olson & Bear LLP
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/40
Abstract:
Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
Public/Granted literature
- US20140357852A1 NUCLEIC ACID ENCODING ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) Public/Granted day:2014-12-04
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