发明授权
US08981089B2 Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors
有权
吡唑并喹唑啉衍生物，其制备方法及其作为激酶抑制剂的用途
- 专利标题： Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors
- 专利标题（中）： 吡唑并喹唑啉衍生物，其制备方法及其作为激酶抑制剂的用途
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申请号： US13972659申请日： 2013-08-21
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公开(公告)号： US08981089B2公开(公告)日： 2015-03-17
- 发明人: Gabriella Traquandi , Maria Gabriella Brasca , Roberto D'Alessio , Paolo Polucci , Fulvia Roletto , Anna Vulpetti , Paolo Pevarello , Achille Panzeri , Francesca Quartieri , Ron Ferguson , Paola Vianello , Daniele Fancelli
- 申请人： Gabriella Traquandi , Maria Gabriella Brasca , Roberto D'Alessio , Paolo Polucci , Fulvia Roletto , Anna Vulpetti , Paolo Pevarello , Achille Panzeri , Francesca Quartieri , Ron Ferguson , Paola Vianello , Daniele Fancelli
- 申请人地址： IT Nerviano, Milan
- 专利权人： Nerviano Medical Sciences S.R.L.
- 当前专利权人： Nerviano Medical Sciences S.R.L.
- 当前专利权人地址： IT Nerviano, Milan
- 代理机构： Scully, Scott, Murphy & Presser, P.C.
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; C07D403/14 ; C07D413/14 ; C07D487/14 ; C07D231/56 ; C07D239/72
摘要：
Pyrazolo-quinazoline derivatives of formula (Ia) or (Ib) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
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