Invention Grant
US08981089B2 Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors
有权
吡唑并喹唑啉衍生物，其制备方法及其作为激酶抑制剂的用途
- Patent Title: Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors
- Patent Title (中): 吡唑并喹唑啉衍生物，其制备方法及其作为激酶抑制剂的用途
-
Application No.: US13972659Application Date: 2013-08-21
-
Publication No.: US08981089B2Publication Date: 2015-03-17
- Inventor: Gabriella Traquandi , Maria Gabriella Brasca , Roberto D'Alessio , Paolo Polucci , Fulvia Roletto , Anna Vulpetti , Paolo Pevarello , Achille Panzeri , Francesca Quartieri , Ron Ferguson , Paola Vianello , Daniele Fancelli
- Applicant: Gabriella Traquandi , Maria Gabriella Brasca , Roberto D'Alessio , Paolo Polucci , Fulvia Roletto , Anna Vulpetti , Paolo Pevarello , Achille Panzeri , Francesca Quartieri , Ron Ferguson , Paola Vianello , Daniele Fancelli
- Applicant Address: IT Nerviano, Milan
- Assignee: Nerviano Medical Sciences S.R.L.
- Current Assignee: Nerviano Medical Sciences S.R.L.
- Current Assignee Address: IT Nerviano, Milan
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D403/14 ; C07D413/14 ; C07D487/14 ; C07D231/56 ; C07D239/72
Abstract:
Pyrazolo-quinazoline derivatives of formula (Ia) or (Ib) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
Public/Granted literature
- US20130338148A1 PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS Public/Granted day:2013-12-19
Information query
