发明授权
US09045468B2 2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
有权
2,5-亚甲基和2,5-乙基 - 四氢苯并氮杂衍生物及其用于阻断去甲肾上腺素，多巴胺和5-羟色胺的再摄取
- 专利标题： 2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
- 专利标题（中）： 2,5-亚甲基和2,5-乙基 - 四氢苯并氮杂衍生物及其用于阻断去甲肾上腺素，多巴胺和5-羟色胺的再摄取
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申请号： US13211678申请日： 2011-08-17
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公开(公告)号： US09045468B2公开(公告)日： 2015-06-02
- 发明人: Peter R. Guzzo , Shuang Liu , Kristen N. Ryan , Bruce F. Molino , Russell DeOrazio , Richard E. Olson , John E. Macor
- 申请人： Peter R. Guzzo , Shuang Liu , Kristen N. Ryan , Bruce F. Molino , Russell DeOrazio , Richard E. Olson , John E. Macor
- 申请人地址： US NY Albany US NJ Princeton
- 专利权人： Albany Molecular Research, Inc.,Bristol-Myers Squibb Company
- 当前专利权人： Albany Molecular Research, Inc.,Bristol-Myers Squibb Company
- 当前专利权人地址： US NY Albany US NJ Princeton
- 代理机构： LeClairRyan, a Professional Corporation
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; C07D453/00 ; C07D519/00
摘要：
The compounds of the present invention are represented by the following 2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives having formula (I): where the carbon atom designated * is in the R or S configuration when n is 1 and the substituents X and R1-R7 are as defined herein.
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