发明授权
US09051253B2 Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's
有权
用于治疗淀粉样蛋白病和突触核蛋白病如阿尔茨海默病,2型糖尿病和帕金森病的化合物,组合物和方法
- 专利标题: Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's
- 专利标题(中): 用于治疗淀粉样蛋白病和突触核蛋白病如阿尔茨海默病,2型糖尿病和帕金森病的化合物,组合物和方法
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申请号: US13887762申请日: 2013-05-06
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公开(公告)号: US09051253B2公开(公告)日: 2015-06-09
- 发明人: Alan D. Snow , Beth Nguyen , Gerardo Castillo , Virginia Sanders , Thomas Lake , Lesley Larsen
- 申请人: Alan D. Snow , Beth Nguyen , Gerardo Castillo , Virginia Sanders , Thomas Lake , Lesley Larsen
- 申请人地址: US WA Kirkland
- 专利权人: PROTEOTECH INC.
- 当前专利权人: PROTEOTECH INC.
- 当前专利权人地址: US WA Kirkland
- 代理商 Rebecca Eagen
- 主分类号: A61K31/047
- IPC分类号: A61K31/047 ; A61K31/05 ; C07C49/248 ; C07C39/15 ; C07C39/16 ; C07C39/17 ; C07C45/62 ; C07C45/64 ; C07C49/83 ; C07C49/835 ; C07C69/017 ; C07C215/50 ; C07C231/02 ; C07C235/34 ; C07C235/38 ; C07C235/48 ; C07C235/54 ; C07C235/56 ; C07C237/22 ; C07C275/34 ; C07D207/16 ; C07D211/74 ; C07D213/30 ; C07D213/69 ; C07D213/85 ; C07D221/08 ; C07D221/18 ; C07D231/06 ; C07D241/08 ; C07D263/38 ; C07D265/38 ; C07D295/096 ; C07D295/192 ; C07D311/60 ; C07D317/50 ; C07D317/54 ; C07D317/58 ; C07D317/60 ; C07D317/66 ; C07D317/68 ; C07D333/16 ; C07D405/14 ; C07D407/14 ; C07D409/14 ; C07D413/14 ; C07D451/06 ; C07D471/04 ; C07D487/08 ; C07D491/08
摘要:
The use of 3,4,3′,4′-tetrahydroxychalcone in the treatment of amyloid diseases, especially Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease.
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