Invention Grant
US09056916B2 Method and assay kit for detection of toxicity induced by pyrrolizidine alkaloids
有权
用于检测由吡咯并三嗪生物碱诱导的毒性的方法和测定试剂盒
- Patent Title: Method and assay kit for detection of toxicity induced by pyrrolizidine alkaloids
- Patent Title (中): 用于检测由吡咯并三嗪生物碱诱导的毒性的方法和测定试剂盒
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Application No.: US13354341Application Date: 2012-01-20
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Publication No.: US09056916B2Publication Date: 2015-06-16
- Inventor: Ge Lin , Jiang Zheng , Na Li
- Applicant: Ge Lin , Jiang Zheng , Na Li
- Applicant Address: CN Hong Kong
- Assignee: THE CHINESE UNIVERSITY OF HONG KONG
- Current Assignee: THE CHINESE UNIVERSITY OF HONG KONG
- Current Assignee Address: CN Hong Kong
- Agency: Duane Morris LLP
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K1/04 ; C07K16/44 ; G01N33/53 ; G01N33/567
Abstract:
An antibody, which specifically recognizes adducts between pyrrole and cellular macromolecules. Such adducts are likely to occur in mammals suffering an incident of pyrrolizidine alkaloid poisoning. The antibody can be produced using a synthetic immunogen conjugated with a pyrrole as a hapten and it can be used, for example in an assay kit and/or by itself, as a novel means for detecting or diagnosing pyrrolizidine alkaloid poisoning both clinics and research laboratories.
Public/Granted literature
- US20130189710A1 Method And Assay Kit For Detection Of Toxicity Induced By Pyrrolizidine Alkaloids Public/Granted day:2013-07-25
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