Invention Grant
- Patent Title: Method for manufacturing optically active menthol
- Patent Title (中): 光学活性薄荷醇的制造方法
-
Application No.: US13990872Application Date: 2011-12-01
-
Publication No.: US09061959B2Publication Date: 2015-06-23
- Inventor: Hironori Maeda , Hisanori Itoh , Shinya Yamada , Yoji Hori
- Applicant: Hironori Maeda , Hisanori Itoh , Shinya Yamada , Yoji Hori
- Applicant Address: JP Tokyo
- Assignee: TAKASAGO INTERNATIONAL CORPORATION
- Current Assignee: TAKASAGO INTERNATIONAL CORPORATION
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2010-268633 20101201
- International Application: PCT/JP2011/077857 WO 20111201
- International Announcement: WO2012/074075 WO 20120607
- Main IPC: C07C29/132
- IPC: C07C29/132 ; C07B53/00 ; C07C29/17 ; C07C29/56 ; B01J31/18 ; B01J31/26 ; B01J21/18 ; B01J23/44

Abstract:
An object of the present invention is to provide a method for manufacturing an optically active menthol having fewer steps, which generates less environmentally polluting waste because a catalytic reaction is involved in all of the steps, and is capable of saving a production cost. The present invention relates to a method for manufacturing an optically active menthol, including the following steps: A-1) asymmetrically hydrogenating at least one of geranial and neral to thereby obtain an optically active citronellal, B-1) conducting a ring-closure reaction of the optically active citronellal in the presence of an acid catalyst to thereby obtain an optically active isopulegol, and C-1) hydrogenating the optically active isopulegol to thereby obtain an optically active menthol.
Public/Granted literature
- US20130253228A1 METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL Public/Granted day:2013-09-26
Information query