公开(公告)号：US08580991B2

公开(公告)日：2013-11-12

申请号：US13140356

申请日：2009-12-17

申请人： Hisanori Itoh ,  Yoji Hori

发明人： Hisanori Itoh ,  Yoji Hori

IPC分类号： C07D305/00 ,  C07F5/06

CPC分类号： C07F5/069 ,  C07B2200/07 ,  C07C29/56 ,  C07C2601/14 ,  C07C35/17

摘要： To provide a process for increasing the proportion of an optical isomer of not only a compound having a closed ring but also a compound not having a closed ring when an optical isomer mixture of a compound having both a formyl group and a double bond capable of causing a carbonyl-ene ring closing reaction in the same molecule is subjected to a ring closing reaction. A process for increasing the proportion of an optical isomer characterized by subjecting an optical isomer mixture of a compound having both a formyl group and a double bond capable of causing a carbonyl-ene ring closing reaction in the same molecule to a ring closing reaction in the presence of a predetermined aluminum complex represented by the general formula: [Al2(L1)n(L2)3-n]m.

摘要翻译： 为了提供不仅具有封闭环的化合物的光学异构体的比例而且当具有甲酰基和双键的化合物的光学异构体混合物能够引起 在相同分子中的羰基 - 烯环闭合反应进行闭环反应。 一种增加光学异构体比例的方法，其特征在于使具有能够在同一分子中引起羰基 - 烯环闭合反应的甲酰基和双键的化合物的旋光异构体混合物在 由通式[Al2（L1）n（L2）3-n] m表示的预定铝络合物的存在。

公开(公告)号：US08329930B2

公开(公告)日：2012-12-11

申请号：US12991967

申请日：2009-05-25

申请人： Hisanori Itoh ,  Yoji Hori

发明人： Hisanori Itoh ,  Yoji Hori

IPC分类号： C07F5/06 ,  C07C35/08

CPC分类号： C07C39/235 ,  C07B53/00 ,  C07B2200/07 ,  C07C29/56 ,  C07C45/67 ,  C07C2601/14 ,  C07F5/069 ,  C07C35/17 ,  C07C47/21

摘要： Provided is a process in which cyclization of a compound having, in a molecule, a formyl group and a double bond which allow carbonyl-ene cyclization, the compound existing as a mixture of optical isomers thereof, increases the ratio of a particular optical isomer not only in a cyclized compound, but also in an unreacted compound. The process comprises performing, in the presence of a specified aluminum complex represented by the general formula: [Al2(L1)n(L2)3-n]m, cyclization of a compound having, in a molecule, a formyl group and a double bond which allow carbonyl-ene cyclization, the compound existing as a mixture of optical isomers thereof, to increase the ratio of a particular optical isomer.

摘要翻译： 提供一种方法，其中在分子中使具有允许羰基环环化的甲酰基和双键的化合物作为其光学异构体的混合物存在的化合物的环化增加了特定光学异构体的比例 仅在环化化合物中，而且在未反应的化合物中。 该方法包括在由通式[Al2（L1）n（L2）3-n] m表示的规定的铝络合物的存在下进行，分子中具有甲酰基和双 允许羰基环环化的键，作为其光学异构体的混合物存在的化合物，以增加特定光学异构体的比例。

公开(公告)号：US20110082308A1

公开(公告)日：2011-04-07

申请号：US12991967

申请日：2009-05-25

申请人： Hisanori Itoh ,  Yoji Hori

发明人： Hisanori Itoh ,  Yoji Hori

IPC分类号： C07C29/00 ,  C07F5/06

CPC分类号： C07C39/235 ,  C07B53/00 ,  C07B2200/07 ,  C07C29/56 ,  C07C45/67 ,  C07C2601/14 ,  C07F5/069 ,  C07C35/17 ,  C07C47/21

摘要： Provided is a process in which cyclization of a compound having, in a molecule, a formyl group and a double bond which allow carbonyl-ene cyclization, the compound existing as a mixture of optical isomers thereof, increases the ratio of a particular optical isomer not only in a cyclized compound, but also in an unreacted compound. The process comprises performing, in the presence of a specified aluminum complex represented by the general formula: [Al2(L1)n(L2)3-m]m, cyclization of a compound having, in a molecule, a formyl group and a double bond which allow carbonyl-ene cyclization, the compound existing as a mixture of optical isomers thereof, to increase the ratio of a particular optical isomer.

摘要翻译： 提供一种方法，其中在分子中使具有允许羰基环环化的甲酰基和双键的化合物作为其光学异构体的混合物存在的化合物的环化增加了特定光学异构体的比例 仅在环化化合物中，而且在未反应的化合物中。 该方法包括在由通式[Al2（L1）n（L2）3-m] m表示的规定的铝络合物的存在下进行，分子中具有甲酰基和双 允许羰基环环化的键，作为其光学异构体的混合物存在的化合物，以增加特定光学异构体的比例。

公开(公告)号：US20100324338A1

公开(公告)日：2010-12-23

申请号：US12792016

申请日：2010-06-02

申请人： Hironori MAEDA ,  Yoji HORI

发明人： Hironori MAEDA ,  Yoji HORI

IPC分类号： C07C45/62 ,  B01J31/02 ,  C07C29/17

CPC分类号： C07D207/06 ,  B01J31/181 ,  B01J2231/645 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/824 ,  B01J2531/827 ,  B01J2531/828 ,  B01J2531/847 ,  C07B53/00 ,  C07B2200/07 ,  C07C45/62 ,  C07D207/08 ,  C07D207/16 ,  C07D233/32 ,  C07D241/44 ,  C07D405/04 ,  C07C47/21

摘要： This invention aims at providing a catalyst for producing an optically active aldehyde or an optically active ketone, which is an optically active carbonyl compound, by carrying out selective asymmetric hydrogenation of an α,β-unsaturated carbonyl compound, particularly a catalyst which is insoluble in a reaction mixture for obtaining optically active citronellal which is useful as a flavor or fragrance, by carrying out selective asymmetric hydrogenation of citral, geranial or neral; and a method for producing a corresponding optically active carbonyl compound. The invention relates to a catalyst for asymmetric hydrogenation of an α,β-unsaturated carbonyl compound, which comprises a powder of at least one metal selected from metals belonging to Group 8 to Group 10 of the Periodic Table, or a metal-supported substance in which at least one metal selected from metals belonging to Group 8 to Group 10 of the Periodic Table is supported on a support, an optically active cyclic nitrogen-containing compound and an acid.

摘要翻译： 本发明的目的在于提供一种用于制备光学活性醛或光学活性酮的催化剂，它是光学活性的羰基化合物，通过进行α，bgr-不饱和羰基化合物的选择性不对称氢化，特别是不溶于 在用于获得可用作香料或香料的光学活性香茅醛的反应混合物中，通过进行柠檬醛，香叶醛或香精的选择性不对称氢化; 以及制备相应的光学活性羰基化合物的方法。 本发明涉及一种α，β-不饱和羰基化合物的不对称氢化催化剂，它包括选自属于元素周期表第8至第10族金属的至少一种金属的粉末或金属负载物质 其中选自属于元素周期表第8族至第10族的金属中的至少一种金属负载在载体上，光学活性环状含氮化合物和酸。

公开(公告)号：US07619003B2

公开(公告)日：2009-11-17

申请号：US10546858

申请日：2004-01-28

申请人： Makoto Tokunaga ,  Yasushi Tsuji ,  Yasushi Obora ,  Yoji Hori ,  Hiroshi Aoyama

发明人： Makoto Tokunaga ,  Yasushi Tsuji ,  Yasushi Obora ,  Yoji Hori ,  Hiroshi Aoyama

IPC分类号： A61K31/045 ,  A61K31/19

CPC分类号： C07C29/10 ,  B01J31/182 ,  B01J31/189 ,  B01J31/2243 ,  B01J31/2409 ,  B01J2531/0241 ,  B01J2531/0252 ,  B01J2531/0266 ,  B01J2531/28 ,  B01J2531/824 ,  B01J2531/828 ,  B01J2531/845 ,  C07B53/00 ,  C07C35/08 ,  C07C35/12 ,  C07C35/30

摘要： A process for producing an optically active compound based on the hydrolysis of an alkenyl ester compound or the cleavage of an alkenyl ether compound. The process uses neither an acidic compound nor a basic compound, and reactants can be reacted in a high concentration. It does not necessitate a buffer, nutrient, etc. unlike enzymatic reactions or reactions using a microorganism. It is a simple process which attains a satisfactory production efficiency. The process, which is for producing an optically active carboxylic acid or optically active alcohol represented by the general formula (VI): (wherein R1, R2, and R3 are different groups; and A represents methylene, carbonyl, or a single bond), is characterized by causing water to act on an alkenyl ester or alkenyl ether represented by the general formula (I): (wherein R4, R5, and R6 each represents hydrogen, alkyl, etc.) in the presence of a specific transition metal complex having an optically active ligand.

摘要翻译： 基于链烯基酯化合物的水解或烯基醚化合物的裂解来制造光学活性化合物的方法。 该方法既不使用酸性化合物也不使用碱性化合物，并且反应物可以高浓度反应。 与使用微生物的酶反应或反应不同，不需要缓冲液，营养物等。 这是一个达到令人满意的生产效率的简单过程。 该方法用于制备由通式（VI）表示的光学活性羧酸或光学活性醇：（其中R 1，R 2和R 3是不同基团; A代表亚甲基，羰基或单键）， 其特征在于使水作用于由通式（I）表示的烯基酯或链烯基醚：（其中R 4，R 5和R 6各自表示氢，烷基等），在具有 光学活性配体。

公开(公告)号：US20070117993A1

公开(公告)日：2007-05-24

申请号：US10581537

申请日：2004-11-24

申请人： Yoji Hori ,  Junji Nakamura ,  Tomoya Sawaki ,  Shigeru Tanaka

发明人： Yoji Hori ,  Junji Nakamura ,  Tomoya Sawaki ,  Shigeru Tanaka

IPC分类号： C07D301/12

CPC分类号： B01J23/30 ,  B01J27/053 ,  B01J27/188 ,  B01J31/0239 ,  B01J2231/72 ,  C07D301/12 ,  C07D303/14 ,  C07D495/08

摘要： A novel multicomponent oxidation catalyst that can be effectively used in, for example, an epoxidation reaction of olefins, etc., being inexpensive and high in versatility and that exhibits high catalytic activity; and a process for producing an epoxy compound through hydrogen peroxide oxidation of an olefin with the use of the multicomponent oxidation catalyst. There is provided a multicomponent oxidation catalyst comprising a tungsten compound, a quaternary ammonium salt, any of phosphoric acids and/or boric acids and a hydrogen sulfate salt. Further, there is provided a process for producing an epoxy compound, characterized in that an olefin is oxidized with hydrogen peroxide in the presence of the above multicomponent oxidation catalyst. The epoxy compound obtained by this process is useful as an intermediate of agricultural chemicals, medicines or the like, a raw material of various polymers, etc.

摘要翻译： 可有效用于例如烯烃等的环氧化反应的新颖的多组分氧化催化剂成本低廉，通用性高，催化活性高; 以及通过使用多组分氧化催化剂通过烯烃的过氧化氢氧化生产环氧化合物的方法。 提供了包含钨化合物，季铵盐，磷酸和/或硼酸中的任一种和硫酸氢盐的多组分氧化催化剂。 此外，提供了一种制备环氧化合物的方法，其特征在于在上述多组分氧化催化剂存在下，用过氧化氢氧化烯烃。 通过该方法获得的环氧化合物可用作农药，药物等的中间体，各种聚合物的原料等。

公开(公告)号：US07105684B2

公开(公告)日：2006-09-12

申请号：US10899965

申请日：2004-07-26

申请人： Tomoya Sawaki ,  Hiroyuki Kenmochi ,  Yoji Hori

发明人： Tomoya Sawaki ,  Hiroyuki Kenmochi ,  Yoji Hori

IPC分类号： C07D313/00 ,  C07D493/08 ,  C07D307/77 ,  C07C69/74

CPC分类号： C07D307/00

摘要： An object of the present invention is to provide a novel monomer compound having a lactone structure which gives polymers having more excellent feature as resist material, etc.The present invention relates to a compound represented by the following formula [1]: wherein R1 and R2 are an alkyl group; R3 and R4 are each independently hydrogen atom or an alkyl group; R5 is hydrogen atom, acryloyl group or methacryloyl group; and X is a methylene group which may have an alkyl group or an ethylene group which may have an alkyl group. The present invention provides a compound having a lactone structure which gives a polymer having more excellent feature particularly as a resist material and also provides a hydroxy lactone being useful as a material, etc. therefor.

摘要翻译： 本发明的目的是提供一种具有内酯结构的新型单体化合物，其具有赋予作为抗蚀剂材料等优异特性的聚合物等。本发明涉及由下式[1]表示的化合物：其中R ^{1 和R 2是烷基; R 3和R 4各自独立地为氢原子或烷基; R 5是氢原子，丙烯酰基或甲基丙烯酰基; X为可以具有烷基的亚甲基或可具有烷基的亚乙基。 本发明提供了具有内酯结构的化合物，其特别是作为抗蚀剂材料得到具有更优异特征的聚合物，并且还提供可用作材料的羟基内酯等。}

公开(公告)号：US20060173210A1

公开(公告)日：2006-08-03

申请号：US10546858

申请日：2004-01-28

申请人： Makoto Tokunaga ,  Yasushi Tsuji ,  Yasushi Obora ,  Yoji Hori ,  Hiroshi Aoyama

发明人： Makoto Tokunaga ,  Yasushi Tsuji ,  Yasushi Obora ,  Yoji Hori ,  Hiroshi Aoyama

IPC分类号： C07C51/09 ,  C07F15/00

CPC分类号： C07C29/10 ,  B01J31/182 ,  B01J31/189 ,  B01J31/2243 ,  B01J31/2409 ,  B01J2531/0241 ,  B01J2531/0252 ,  B01J2531/0266 ,  B01J2531/28 ,  B01J2531/824 ,  B01J2531/828 ,  B01J2531/845 ,  C07B53/00 ,  C07C35/08 ,  C07C35/12 ,  C07C35/30

摘要： A process for producing an optically active compound based on the hydrolysis of an alkenyl ester compound or the cleavage of an alkenyl ether compound. The process uses neither an acidic compound nor a basic compound, and rectants can be reacted in a high concentration. It does not necessitate a buffer, nutrient, etc. unlike enzymatic reactions or reactions using a microorganism. It is a simple process which attains a satisfactory production efficiency. The process, which is for producing an optically active carboxylic acid or optically active alcohol represented by the general formula (VI): (wherein R1, R2, and R3 are different groups; and A represents methylene, carbonyl, or a single bound), is characterized by causing water to act on an alkenyl ester or alkenyl ether represented by the general formula (I): (wherein R4, R5, and R6 each represents hydrogen, alkyl, etc.) in the presence of a specific transition metal complex having an optically active ligand.

摘要翻译： 基于链烯基酯化合物的水解或烯基醚化合物的裂解来制造光学活性化合物的方法。 该方法既不使用酸性化合物也不使用碱性化合物，并且可以以高浓度反应整流剂。 与使用微生物的酶反应或反应不同，不需要缓冲液，营养物等。 这是一个达到令人满意的生产效率的简单过程。 用于制备由通式（VI）表示的光学活性羧酸或光学活性醇的方法：（其中R 1，R 2，R 2，R 2， 其特征在于使水作用于由通式（I）表示的烯基酯或烯基醚：（其中R 3是不同的基团; A代表亚甲基，羰基或单键） 在具有光学性质的特定过渡金属络合物的存在下，R 4，R 5和R 6各自表示氢，烷基等） 活性配体。

公开(公告)号：US20060094875A1

公开(公告)日：2006-05-04

申请号：US10533303

申请日：2003-10-17

申请人： Hisanori Itoh ,  Yuji Nakayama ,  Yoshimasa Matsushima ,  Yoji Hori

发明人： Hisanori Itoh ,  Yuji Nakayama ,  Yoshimasa Matsushima ,  Yoji Hori

IPC分类号： C07F15/00 ,  H01L51/54 ,  C09K11/06

CPC分类号： C07F15/0093 ,  C07D213/53 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1029 ,  C09K2211/1033 ,  C09K2211/1037 ,  C09K2211/1044 ,  C09K2211/1088 ,  C09K2211/1092 ,  C09K2211/185 ,  H01L51/0087 ,  H01L51/5016 ,  H01L51/5048 ,  H01L51/5096

摘要： The invention aims at providing platinum complexes useful as materials for light emitting devices and extremely excellent in heat stability, luminous characteristics, and luminous efficiency, and a process for effective preparation thereof. The invention relates to platinum complexes represented by the general formula [1]: wherein any two of A, B and C are each independently an optionally substituted nitrogenous aromatic heterocyclic group and the other is optionally substituted aryl or optionally substituted heteroaryl; and Y is halogeno or an optionally substituted aryl or heteroaryl group which is bonded either directly or through oxygen (—O—) or sulfur (—S—) (with the proviso that when the adjacent two rings are nitrogenous aromatic heterocyclic groups, the cases wherein Y is chloro are excepted, while when the nonadjacent two rings are nitrogenous aromatic heterocyclic groups, the cases wherein Y is not halogeno are excepted).

摘要翻译： 本发明旨在提供可用作发光器件材料的铂络合物，并且热稳定性，发光特性和发光效率极好，以及其制备方法。 本发明涉及由通式[1]表示的铂络合物：其中A，B和C中的任何两个各自独立地为任选取代的含氮芳族杂环基，另一个为任选取代的芳基或任选取代的杂芳基; Y为卤素或任选取代的芳基或杂芳基，其直接或通过氧（-O-）或硫（-S-）键合（条件是当相邻的两个环为含氮芳族杂环基时） 其中Y为氯的除外，而当不相邻的两个环为含氮芳族杂环基时，除了Y不是卤素的情况外）。

公开(公告)号：US06365776B1

公开(公告)日：2002-04-02

申请号：US09946468

申请日：2001-09-06

申请人： Mitsuhiko Fujiwara ,  Ken Suzuki ,  Tohru Kobayashi ,  Yoji Hori ,  Toshimitsu Hagiwara

发明人： Mitsuhiko Fujiwara ,  Ken Suzuki ,  Tohru Kobayashi ,  Yoji Hori ,  Toshimitsu Hagiwara

IPC分类号： C07C21100

CPC分类号： C07C209/10 ,  C07C211/54

摘要： The present invention provides an activator in arylamination using a palladium compound as a catalyst, which is superior to conventional phosphines in stability and performance. With the phosphine sulfide as an activator, an arylamination reaction achieves improved selectivity to produce a desired aromatic amine in an obviously increased yield as compared with a reaction using the corresponding phosphine compound. Moreover, the phosphine sulfide of the invention is impervious to oxidation and exists stably in air and therefore sufficiently withstands use on an industrial scale.

摘要翻译： 本发明提供使用钯化合物作为催化剂的芳基化活化剂，其在稳定性和性能方面优于常规膦。 与使用相应的膦化合物的反应相比，以硫化氢作为活化剂，芳基化反应实现了以明显增加的产率产生所需芳族胺的选择性。 此外，本发明的硫化膦不能氧化，在空气中稳定地存在，因此能够充分地耐受工业规模的使用。