Invention Grant
- Patent Title: Method for deblocking of labeled oligonucleotides
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Application No.: US13964036Application Date: 2013-08-09
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Publication No.: US09085797B2Publication Date: 2015-07-21
- Inventor: Gulilat Gebeyehu , Richard Pires
- Applicant: LIFE TECHNOLOGIES CORPORATION
- Applicant Address: US CA Carlsbad
- Assignee: Life Technologies Corporation
- Current Assignee: Life Technologies Corporation
- Current Assignee Address: US CA Carlsbad
- Main IPC: C07H21/00
- IPC: C07H21/00 ; C12Q1/68
Abstract:
The invention relates to a process for deblocking substantially a blocked, detectably labeled oligonucleotide by contacting the blocked detectably labeled oligonucleotide with an effective amount of a nucleophilic amino compound under conditions that result in substantial deblocking of the oligonucleotide, thereby giving the substantially deblocked oligonucleotide.
Public/Granted literature
- US20140066612A1 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES Public/Granted day:2014-03-06
Information query
