Invention Grant
- Patent Title: Triazone compounds that modulate HSP90 activity
- Patent Title (中): 调节HSP90活性的三嗪类化合物
-
Application No.: US12604970Application Date: 2009-10-23
-
Publication No.: US09090569B2Publication Date: 2015-07-28
- Inventor: Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Junghyun Chae , Dinesh U. Chimmanamada , Chi-Wan Lee , Elena Kostik , Howard P. Ng , Kevin Foley , Zhenjian Du , James Barsoum
- Applicant: Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Junghyun Chae , Dinesh U. Chimmanamada , Chi-Wan Lee , Elena Kostik , Howard P. Ng , Kevin Foley , Zhenjian Du , James Barsoum
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Emily Dertz
- Main IPC: A61K31/4196
- IPC: A61K31/4196 ; C07D249/08 ; C07D249/12 ; C07D401/04 ; C07D403/04 ; C07D403/10 ; C07D405/04 ; C07D409/04 ; C07D413/04 ; C07D417/04 ; C07D473/00 ; C07D473/34
Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Public/Granted literature
- US20110009397A1 TRIAZONE COMPOUNDS THAT MODULATE HSP90 ACTIVITY Public/Granted day:2011-01-13
Information query
