Invention Grant
US09109029B2 Compositions comprising soluble CD84 or anti-CD84 antibodies and methods for diagnosing and treating B-CLL
有权
包含可溶性CD84或抗CD84抗体的组合物和用于诊断和治疗B-CLL的方法
- Patent Title: Compositions comprising soluble CD84 or anti-CD84 antibodies and methods for diagnosing and treating B-CLL
- Patent Title (中): 包含可溶性CD84或抗CD84抗体的组合物和用于诊断和治疗B-CLL的方法
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Application No.: US14172926Application Date: 2014-02-05
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Publication No.: US09109029B2Publication Date: 2015-08-18
- Inventor: Idit Shachar , Inbal Binsky , Mirko Sobotta
- Applicant: Yeda Research and Development Co. Ltd.
- Applicant Address: IL Rehovot
- Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee Address: IL Rehovot
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/00 ; C07K16/28 ; C07K14/705 ; G01N33/574 ; C12Q1/68 ; A61K38/00
Abstract:
A method of diagnosing B-CLL in a subject in need thereof is provided. The method comprising determining in a biological sample of the subject a level of CD84 isoform C (SEQ ID NO: 30), wherein an increase in the level of the CD84 isoform C (SEQ ID NO: 30) beyond a predetermined threshold with respect to a level of the CD84 in a biological sample from a healthy individual is indicative of the B-CLL.
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