Invention Grant
US09133145B2 Methods of use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
有权
11-β-羟基类固醇脱氢酶1型酶抑制剂的使用方法
- Patent Title: Methods of use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
- Patent Title (中): 11-β-羟基类固醇脱氢酶1型酶抑制剂的使用方法
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Application No.: US13782054Application Date: 2013-03-01
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Publication No.: US09133145B2Publication Date: 2015-09-15
- Inventor: R. Scott Bitner , Kaitlin E. Browman , Michael E. Brune , Steven X. Fung , Peer B. Jacobson , Lynne E. Rueter , Marina I. Strakhova , Jiahong Wang , James T. Link , Yixian Chen , Hwan-soo Jae , Jyoti R. Patel , Marina A. Pliushchev , Jeffrey J. Rohde , Qi Shuai , Bryan K. Sorensen , Martin Winn , Dariusz Wodka , Hong Yong
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agency: Michael Best & Friedrich LLP
- Agent Lisa V. Mueller
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/55 ; C07D295/155 ; C07D205/04 ; C07D207/12 ; C07D209/44 ; C07D211/42 ; C07D213/72 ; C07D231/12 ; C07D239/42 ; A61K31/5375 ; C07D277/82 ; C07D295/125 ; C07D307/68 ; C07D401/04 ; C07D401/12 ; C07D413/12 ; C07D487/04 ; C07D491/056
Abstract:
The present invention relates to inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids.
Public/Granted literature
- US20130338169A1 METHODS OF USE OF INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME Public/Granted day:2013-12-19
Information query
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