Invention Grant
US09133168B2 Pyrimidine derivatives, preparation thereof, and pharmaceutical use thereof as akt(pkb) phosphorylation inhibitors
有权
嘧啶衍生物，其制备方法及其作为akt（pkb）磷酸化抑制剂的药物用途
- Patent Title: Pyrimidine derivatives, preparation thereof, and pharmaceutical use thereof as akt(pkb) phosphorylation inhibitors
- Patent Title (中): 嘧啶衍生物，其制备方法及其作为akt（pkb）磷酸化抑制剂的药物用途
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Application No.: US13977396Application Date: 2011-12-22
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Publication No.: US09133168B2Publication Date: 2015-09-15
- Inventor: Maurice Brollo , Jean-Christophe Carry , Victor Certal , Eric Didier , Gilles Doerflinger , Youssef El Ahmad , Frank Halley , Karl Andreas Karlsson
- Applicant: Maurice Brollo , Jean-Christophe Carry , Victor Certal , Eric Didier , Gilles Doerflinger , Youssef El Ahmad , Frank Halley , Karl Andreas Karlsson
- Applicant Address: FR Paris
- Assignee: SANOFI
- Current Assignee: SANOFI
- Current Assignee Address: FR Paris
- Agency: Morrison & Foerster LLP
- Priority: FR1061297 20101228; FR1061298 20101228; FR1061300 20101228; FR1061301 20101228; FR1061303 20101228; FR1159313 20111014; FR1159315 20111014; FR1159316 20111014; FR1159317 20111014
- International Application: PCT/EP2011/073875 WO 20111222
- International Announcement: WO2012/089633 WO 20120705
- Main IPC: C07D413/14
- IPC: C07D413/14 ; C07D413/04 ; C07D401/04 ; C07D403/06 ; C07D209/30 ; C07D403/04 ; C07D471/10 ; C07D403/14
Abstract:
The present invention relates to novel chemical compounds derived from pyrimidines, to the method for preparing same, to the novel intermediates obtained, to the use thereof as drugs, to the pharmaceutical compositions containing same, and to the therapeutic use thereof as AKT inhibitors.
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