Invention Grant
- Patent Title: Cell culture methods to reduce acidic species
- Patent Title (中): 细胞培养方法减少酸性物种
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Application No.: US13830583Application Date: 2013-03-14
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Publication No.: US09150645B2Publication Date: 2015-10-06
- Inventor: Kartik Subramanian , Xiaobei Zeng , Diane D. Dong , Wen Chung Lim , Kathreen A. Gifford , Christopher Chumsae
- Applicant: ABBVIE INC.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie, Inc.
- Current Assignee: AbbVie, Inc.
- Current Assignee Address: US IL North Chicago
- Agency: McCarter & English, LLP
- Agent Maria Laccotripe Zacharakis; Deborah L. Nagle
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C07K16/24 ; C07K1/16 ; C07K1/18 ; A61K39/395 ; C07K16/00 ; C07K1/20 ; C07K1/22

Abstract:
The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the amount of acidic species expressed by host cells, as well as to compositions and processes for controlling the amount of acidic species present in purified preparations.
Public/Granted literature
- US20140161815A9 CELL CULTURE METHODS TO REDUCE ACIDIC SPECIES Public/Granted day:2014-06-12
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