A system and method for interrupting a transmitting device during a call. In the system, calls are transmitted from a first device on a communication channel as a series of channel frames. At predetermined times during the transmission, the transmitting device is configured to drop channel frames, resulting in open channel frame periods where the transmitting device is not transmitting on the communication channel. During these open channel frame periods, the transmitting device is also configured to switch to a receiving mode. Other devices in the system are capable of switching into a transmitting mode during the open channel frame periods and, when applicable, sending an interrupt request on the communication channel to the transmitting device in order to request access to the channel.