发明授权
US09181401B2 Phosphorylcholine-based amphiphilic silicones for medical applications
有权
用于医疗应用的基于磷酰胆碱的两亲性硅氧烷
- 专利标题： Phosphorylcholine-based amphiphilic silicones for medical applications
- 专利标题（中）： 用于医疗应用的基于磷酰胆碱的两亲性硅氧烷
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申请号： US13378260申请日： 2010-06-07
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公开(公告)号： US09181401B2公开(公告)日： 2015-11-10
- 发明人: James Parakka , Ananth V. Iyer , Anfeng Wang , Xuwei Jiang , Yuan Tian , Robert Ward
- 申请人： James Parakka , Ananth V. Iyer , Anfeng Wang , Xuwei Jiang , Yuan Tian , Robert Ward
- 申请人地址： NL Heerlen
- 专利权人： DSM IP ASSETS B.V.
- 当前专利权人： DSM IP ASSETS B.V.
- 当前专利权人地址： NL Heerlen
- 代理机构： Birch Stewart Kolasch & Birch, LLP
- 国际申请： PCT/US2010/037576 WO 20100607
- 国际公布： WO2010/147779 WO 20101223
- 主分类号： A61L15/24
- IPC分类号： A61L15/24 ; C08L83/08 ; G02B1/04 ; C08F30/02 ; C08F230/02 ; C07F7/02 ; C07F9/02 ; C08G77/395 ; A61L31/10 ; A61L15/26 ; C07F9/6574 ; A61L27/34 ; C08F230/08 ; C07F9/09 ; A61F13/00 ; A61L27/18 ; C08L83/10 ; A61L26/00
摘要：
Amphiphilic biomimetic phosphorylcholine-containing silicone compounds for use in both topical and internal applications as components in biomedical devices. The silicone compounds, which include zwitterionic phosphorylcholine groups, may be polymerizable or non-polymerizable. Specific examples of applications include use as active functional components in ophthalmic lenses, ophthalmic lens care solutions, liquid bandages, wound dressings, and lubricious and anti-thrombogenic coatings.