Invention Grant
- Patent Title: Methods to modulate lysine variant distribution
- Patent Title (中): 调节赖氨酸变体分布的方法
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Application No.: US13830976Application Date: 2013-03-14
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Publication No.: US09181572B2Publication Date: 2015-11-10
- Inventor: Kartik Subramanian , Mayda Perez , Xiaobei Zeng , Chee Furng Wong , Christopher Chumsae
- Applicant: ABBVIE INC.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie, Inc.
- Current Assignee: AbbVie, Inc.
- Current Assignee Address: US IL North Chicago
- Agency: McCarter & English, LLP
- Agent Maria Laccotripe Zacharakis; Deborah L. Nagle
- Main IPC: C12P21/08
- IPC: C12P21/08 ; C12P21/00 ; C07K16/00 ; C07K16/28 ; C12N5/00
Abstract:
The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the distribution or amount of lysine variants expressed by host cells, as well as to compositions and processes for controlling the amount of lysine variants present in purified preparations.
Public/Granted literature
- US20130280274A1 METHODS TO MODULATE LYSINE VARIANT DISTRIBUTION Public/Granted day:2013-10-24
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