Inhibition of enzymes

Invention Grant

US09199984B2 Inhibition of enzymes 有权

Title translation: 抑制酶

Patent Title: Inhibition of enzymes
Patent Title (中): 抑制酶
Application No.: US13940555

Application Date: 2013-07-12
Publication No.: US09199984B2

Publication Date: 2015-12-01
Inventor: Carmelida Capaldi , Robert Andrew Heald , Nicholas Charles Ray , Jonathan Mark Sutton
Applicant: CHIESI FARMACEUTICI S.p.A.
Applicant Address: IT Parma
Assignee: CHIESI FARMACEUTICI S.p.A.
Current Assignee: CHIESI FARMACEUTICI S.p.A.
Current Assignee Address: IT Parma
Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
Priority: EP12176079 20120712; EP13158756 20130312
Main IPC: C07D401/02
IPC: C07D401/02 ; C07D401/10 ; C07D401/14 ; A61K31/4353 ; A61K31/437 ; C07D471/04

Abstract:

Compounds of formula (I): wherein R1, R2, R3, R5, R6, A1, A2, A3, A4 assume meanings as defined in formula (I) are inhibitors of neutrophil elastase.

Abstract(Chinese):

式（I）化合物：其中R 1，R 2，R 3，R 5，R 6，A 1，A 2，A 3，A 4定义为式（I）中定义的含义是嗜中性粒细胞弹性蛋白酶抑制剂。

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IPC分类:

C	化学；冶金
C07	有机化学
C07D	杂环化合物（高分子化合物入C08）
C07D401/00	杂环化合物，含有两个或更多个杂环，以氮原子作为仅有的杂环原子，至少有1个环是仅含有1个氮原子的六元环
C07D401/02	.含有两个杂环