Invention Grant
US09237740B2 Compositions and methods relating to non-human animals modified to promote production of selected gametes
有权
与非人类动物有关的组合物和方法被修改以促进所选配子的产生
- Patent Title: Compositions and methods relating to non-human animals modified to promote production of selected gametes
- Patent Title (中): 与非人类动物有关的组合物和方法被修改以促进所选配子的产生
-
Application No.: US13941014Application Date: 2013-07-12
-
Publication No.: US09237740B2Publication Date: 2016-01-19
- Inventor: Michael V. Wiles , Robert Taft
- Applicant: The Jackson Laboratory
- Applicant Address: US ME Bar Harbor
- Assignee: The Jackson Laboratory
- Current Assignee: The Jackson Laboratory
- Current Assignee Address: US ME Bar Harbor
- Agency: Dinsmore & Shohl LLP
- Main IPC: C12N15/00
- IPC: C12N15/00 ; A01K67/02 ; A01K67/027 ; C12N15/877 ; C12N15/873
Abstract:
Methods and compositions for producing selected non-human mammalian germ cells and gametes and for making non-human animals using the produced germ cells and gametes are provided by the present invention. Methods of generating a non-human embryo and/or animal derived from donor stem cells, methods of generating chimeric non-human animals having substantially all gametes and/or germ cells derived from the donor stem cells, methods of producing a non-human host embryo lacking functional endogenous germ cells and non-human host embryos incapable of developing endogenous gametes of the present invention are described herein.
Public/Granted literature
Information query
IPC分类:
