发明授权
- 专利标题： Polycyclic HERG activators
- 专利标题（中）： 多环HERG激活剂
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申请号： US14688397申请日： 2015-04-16
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公开(公告)号： US09255093B2公开(公告)日： 2016-02-09
- 发明人: Gregory Raymond Bebernitz , Emma Cody , Tajesh Patel , Ming Qian , Lewis Whitehead , Thomas Zabawa , Frederic Zecri
- 申请人： Gregory Raymond Bebernitz , Emma Cody , Tajesh Patel , Ming Qian , Lewis Whitehead , Thomas Zabawa , Frederic Zecri
- 申请人地址： CH Basel
- 专利权人： NOVARTIS AG
- 当前专利权人： NOVARTIS AG
- 当前专利权人地址： CH Basel
- 代理商 Joshua Roth
- 主分类号： C07D405/04
- IPC分类号： C07D405/04 ; A61K31/41 ; C07D417/12 ; C07D405/14 ; C07D307/85 ; A61K31/343 ; C07D407/12 ; A61K31/357 ; A61K31/443 ; A61K31/428
摘要：
The present invention provides a compound of formula I, in which R1, R2, X and R3 are defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
公开/授权文献
- US20150299181A1 POLYCYCLIC HERG ACTIVATORS 公开/授权日：2015-10-22