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公开(公告)号:US20160108025A1
公开(公告)日:2016-04-21
申请号:US14983741
申请日:2015-12-30
申请人: Gregory Raymond Bebernitz , Emma Cody , Tajesh Patel , Ming Qian , Lewis Whitehead , Thomas Zabawa , Frederic Zecri
发明人: Gregory Raymond Bebernitz , Emma Cody , Tajesh Patel , Ming Qian , Lewis Whitehead , Thomas Zabawa , Frederic Zecri
IPC分类号: C07D405/04 , C07D405/14 , C07D307/85 , A61K31/343 , C07D407/12 , A61K31/36 , A61K31/357 , A61K31/5377 , C07D405/12 , A61K31/443 , C07D417/12 , A61K31/428 , A61K31/4439 , C07D417/14 , A61K31/41
CPC分类号: C07D405/04 , A61K31/343 , A61K31/357 , A61K31/36 , A61K31/41 , A61K31/428 , A61K31/443 , A61K31/4439 , A61K31/5377 , C07D307/85 , C07D405/12 , C07D405/14 , C07D407/12 , C07D417/12 , C07D417/14
摘要: The present invention provides a compound of formula I, in which R1, R2, X and R3 are defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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公开(公告)号:US20150299181A1
公开(公告)日:2015-10-22
申请号:US14688397
申请日:2015-04-16
申请人: Gregory Raymond BEBERNITZ , Emma CODY , Tajesh PATEL , Ming QIAN , Lewis WHITEHEAD , Thomas ZABAWA , Frederic ZECRI
发明人: Gregory Raymond BEBERNITZ , Emma CODY , Tajesh PATEL , Ming QIAN , Lewis WHITEHEAD , Thomas ZABAWA , Frederic ZECRI
IPC分类号: C07D417/12 , A61K31/41 , C07D405/14 , A61K31/428 , A61K31/343 , C07D407/12 , A61K31/357 , A61K31/443 , C07D405/04 , C07D307/85
CPC分类号: C07D405/04 , A61K31/343 , A61K31/357 , A61K31/36 , A61K31/41 , A61K31/428 , A61K31/443 , A61K31/4439 , A61K31/5377 , C07D307/85 , C07D405/12 , C07D405/14 , C07D407/12 , C07D417/12 , C07D417/14
摘要: The present invention provides a compound of formula I, in which R1, R2, X and R3 are defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
摘要翻译: 本发明提供式I化合物或其药学上可接受的盐,其中R 1,R 2,X和R 3在发明概述中定义。 制备本发明化合物的方法及其治疗用途。 本发明还提供药理活性剂和药物组合物的组合。
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公开(公告)号:US09255093B2
公开(公告)日:2016-02-09
申请号:US14688397
申请日:2015-04-16
申请人: Gregory Raymond Bebernitz , Emma Cody , Tajesh Patel , Ming Qian , Lewis Whitehead , Thomas Zabawa , Frederic Zecri
发明人: Gregory Raymond Bebernitz , Emma Cody , Tajesh Patel , Ming Qian , Lewis Whitehead , Thomas Zabawa , Frederic Zecri
IPC分类号: C07D405/04 , A61K31/41 , C07D417/12 , C07D405/14 , C07D307/85 , A61K31/343 , C07D407/12 , A61K31/357 , A61K31/443 , A61K31/428
CPC分类号: C07D405/04 , A61K31/343 , A61K31/357 , A61K31/36 , A61K31/41 , A61K31/428 , A61K31/443 , A61K31/4439 , A61K31/5377 , C07D307/85 , C07D405/12 , C07D405/14 , C07D407/12 , C07D417/12 , C07D417/14
摘要: The present invention provides a compound of formula I, in which R1, R2, X and R3 are defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
摘要翻译: 本发明提供式I化合物或其药学上可接受的盐,其中R 1,R 2,X和R 3在发明概述中定义。 制备本发明化合物的方法及其治疗用途。 本发明还提供药理活性剂和药物组合物的组合。
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