发明授权
US09278966B2 Method for manufacturing oxetane compound, method for manufacturing azolylmethylcyclopentanol compound, and intermediate compound
有权
制备氧杂环丁烷化合物的方法，制备唑基甲基环戊醇化合物的方法和中间体化合物
- 专利标题： Method for manufacturing oxetane compound, method for manufacturing azolylmethylcyclopentanol compound, and intermediate compound
- 专利标题（中）： 制备氧杂环丁烷化合物的方法，制备唑基甲基环戊醇化合物的方法和中间体化合物
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申请号： US14124114申请日： 2012-06-06
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公开(公告)号： US09278966B2公开(公告)日： 2016-03-08
- 发明人: Kazuhiko Sunagawa , Toru Yamazaki , Emiko Obata
- 申请人： Kazuhiko Sunagawa , Toru Yamazaki , Emiko Obata
- 申请人地址： JP Tokyo
- 专利权人： KUREHA CORPORATION
- 当前专利权人： KUREHA CORPORATION
- 当前专利权人地址： JP Tokyo
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： JP2011-127766 20110607
- 国际申请： PCT/JP2012/064601 WO 20120606
- 国际公布： WO2012/169555 WO 20121213
- 主分类号： C07D401/00
- IPC分类号： C07D401/00 ; C07D277/22 ; C07D277/30 ; C07D249/08 ; C07D305/00 ; C07D407/00 ; C07D493/00 ; C07D417/14 ; C07D333/28 ; C07C309/66 ; C07C309/73 ; C07D401/08 ; C07D405/06 ; C07D409/06 ; C07D409/08 ; C07D417/06 ; C07D417/08 ; C07D277/20 ; C07D277/32 ; C07D213/61 ; C07D305/14 ; C07D405/14
摘要：
In order to produce an intermediate from which a cyclic alcohol compound can be stereoselectively obtained, a method for producing an oxetane compound according to the present invention includes the step of reacting, with a cyanide salt, a compound represented by Formula (I): wherein R1 is selected from a hydrogen atom and an alkyl group optionally having a substituent; X1 is selected from a halogen atom and —OSO2R3 where R3 is selected from an alkyl group optionally having a substituent, a phenyl group, and a naphthyl group; and a ring Z1 represents a cyclic hydrocarbon optionally having a substituent, to obtain a compound represented by Formula (II):
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