Invention Grant
US09279012B2 Method of reducing cell death by administering a nucleic acid encoding a paracrine factor of a mesenchymal stem cell
有权
通过施用编码间充质干细胞的旁分泌因子的核酸来减少细胞死亡的方法
- Patent Title: Method of reducing cell death by administering a nucleic acid encoding a paracrine factor of a mesenchymal stem cell
- Patent Title (中): 通过施用编码间充质干细胞的旁分泌因子的核酸来减少细胞死亡的方法
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Application No.: US14256169Application Date: 2014-04-18
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Publication No.: US09279012B2Publication Date: 2016-03-08
- Inventor: Victor J. Dzau , Maria Mirotsou
- Applicant: The Brigham and Women's Hospital, Inc. , Duke University
- Applicant Address: US MA Boston US NC Durham
- Assignee: The Brigham and Women's Hospital, Inc.,Duke University
- Current Assignee: The Brigham and Women's Hospital, Inc.,Duke University
- Current Assignee Address: US MA Boston US NC Durham
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Ingrid A. Beattie
- Main IPC: A61K38/17
- IPC: A61K38/17 ; C07K14/435 ; C07K14/475 ; C12N15/09 ; C12N15/63 ; A61K38/18 ; C12N5/10
Abstract:
A purified paracrine factor of a mesenchymal stem cell, such as a Secreted frizzled related protein (Sfrp) is useful to reduce cell death an/or tissue injury associated with ischemic conditions.
Public/Granted literature
- US20140357703A1 Stem Cell Derived Factors for Treating Pathologic Conditions Public/Granted day:2014-12-04
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