Invention Grant
- Patent Title: Methods of producing adalimumab
- Patent Title (中): 生产阿达木单抗的方法
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Application No.: US14920452Application Date: 2015-10-22
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Publication No.: US09284371B2Publication Date: 2016-03-15
- Inventor: Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-Hsiang D. Chang , Thomas Seewoester
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agency: Foley Hoag LLP
- Main IPC: C07K16/24
- IPC: C07K16/24
Abstract:
The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Public/Granted literature
- US20160039927A1 Cell Culture Improvements Public/Granted day:2016-02-11
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