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公开(公告)号：US20140206038A1
公开(公告)日：2014-07-24
申请号：US14226333
申请日：2014-03-26
Applicant: AbbVie Inc.
Inventor： Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-Hsiang David Chang , Thomas Seewoester
IPC: C07K16/24
CPC classification number: C12N5/0037 , C07K16/00 , C07K16/241 , C07K16/244 , C07K16/2869 , C07K2317/14 , C07K2317/21 , C12N5/0031 , C12N5/0603 , C12N2500/24 , C12N2500/25 , C12N2500/30 , C12N2500/32 , C12N2500/34 , C12N2500/38 , C12N2500/50 , C12N2500/60 , C12N2500/74 , C12N2500/76 , C12N2500/90 , C12N2501/10 , C12N2501/33 , C12N2510/02 , C12N2511/00
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Abstract translation: 本发明描述了用于在哺乳动物细胞培养物中产生重组蛋白例如抗体的改进的方法和组合物。 此外，本发明提供改进的细胞培养基，包括改良的生产培养基，饲料溶液和组合饲料，其可用于改善哺乳动物细胞培养物中的蛋白质生产力。
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公开(公告)号：US20170130191A1
公开(公告)日：2017-05-11
申请号：US15187425
申请日：2016-06-20
Applicant: AbbVie Inc.
Inventor： Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-hsiang D. Chang , Thomas Seewoester
IPC: C12N5/00
CPC classification number: C12N5/0037 , C07K16/00 , C07K16/241 , C07K16/244 , C07K16/2869 , C07K2317/14 , C07K2317/21 , C12N5/0031 , C12N5/0603 , C12N2500/24 , C12N2500/25 , C12N2500/30 , C12N2500/32 , C12N2500/34 , C12N2500/38 , C12N2500/50 , C12N2500/60 , C12N2500/74 , C12N2500/76 , C12N2500/90 , C12N2501/10 , C12N2501/33 , C12N2510/02 , C12N2511/00
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
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公开(公告)号：US09234032B2
公开(公告)日：2016-01-12
申请号：US14157460
申请日：2014-01-16
Applicant: AbbVie Inc.
Inventor： Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-hsiang D. Chang , Thomas Seewoester
CPC classification number: C12N5/0037 , C07K16/00 , C07K16/241 , C07K16/244 , C07K16/2869 , C07K2317/14 , C07K2317/21 , C12N5/0031 , C12N5/0603 , C12N2500/24 , C12N2500/25 , C12N2500/30 , C12N2500/32 , C12N2500/34 , C12N2500/38 , C12N2500/50 , C12N2500/60 , C12N2500/74 , C12N2500/76 , C12N2500/90 , C12N2501/10 , C12N2501/33 , C12N2510/02 , C12N2511/00
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Abstract translation: 本发明描述了用于在哺乳动物细胞培养物中产生重组蛋白例如抗体的改进的方法和组合物。 此外，本发明提供改进的细胞培养基，包括改良的生产培养基，饲料溶液和组合饲料，其可用于改善哺乳动物细胞培养物中的蛋白质生产力。
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公开(公告)号：US10119118B2
公开(公告)日：2018-11-06
申请号：US15187425
申请日：2016-06-20
Applicant: AbbVie Inc.
Inventor： Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-hsiang D. Chang , Thomas Seewoester
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
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公开(公告)号：US20150093784A1
公开(公告)日：2015-04-02
申请号：US14570685
申请日：2014-12-15
Applicant: AbbVie Inc.
Inventor： Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-Hsiang D. Chang , Thomas Seewoester
CPC classification number: C12N5/0037 , C07K16/241 , C07K16/244 , C07K16/2863 , C07K2317/14 , C07K2317/21 , C12N5/0043 , C12N2500/24 , C12N2500/32 , C12N2500/34 , C12N2500/38 , C12N2500/60 , C12N2500/74 , C12N2500/76 , C12N2501/105 , C12N2501/33
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
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Patent Agency Ranking
公开(公告)号：US08906646B2
公开(公告)日：2014-12-09
申请号：US14226333
申请日：2014-03-26
Applicant: AbbVie Inc.
Inventor： Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-Hsiang David Chang , Thomas Seewoester
IPC: G01N1/30 , G01N33/48 , C12P21/04 , C12N5/07 , C12N5/16 , C12N5/10 , C12N5/00 , C12N5/02 , C07K16/24 , C07K16/00
CPC classification number: C12N5/0037 , C07K16/00 , C07K16/241 , C07K16/244 , C07K16/2869 , C07K2317/14 , C07K2317/21 , C12N5/0031 , C12N5/0603 , C12N2500/24 , C12N2500/25 , C12N2500/30 , C12N2500/32 , C12N2500/34 , C12N2500/38 , C12N2500/50 , C12N2500/60 , C12N2500/74 , C12N2500/76 , C12N2500/90 , C12N2501/10 , C12N2501/33 , C12N2510/02 , C12N2511/00
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Abstract translation: 本发明描述了用于在哺乳动物细胞培养物中产生重组蛋白例如抗体的改进的方法和组合物。 此外，本发明提供改进的细胞培养基，包括改良的生产培养基，饲料溶液和组合饲料，其可用于改善哺乳动物细胞培养物中的蛋白质生产力。
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公开(公告)号：US20160039927A1
公开(公告)日：2016-02-11
申请号：US14920452
申请日：2015-10-22
Applicant: AbbVie Inc.
Inventor： Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-Hsiang D. Chang , Thomas Seewoester
IPC: C07K16/24
CPC classification number: C12N5/0037 , C07K16/00 , C07K16/241 , C07K16/244 , C07K16/2869 , C07K2317/14 , C07K2317/21 , C12N5/0031 , C12N5/0603 , C12N2500/24 , C12N2500/25 , C12N2500/30 , C12N2500/32 , C12N2500/34 , C12N2500/38 , C12N2500/50 , C12N2500/60 , C12N2500/74 , C12N2500/76 , C12N2500/90 , C12N2501/10 , C12N2501/33 , C12N2510/02 , C12N2511/00
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
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公开(公告)号：US09090867B2
公开(公告)日：2015-07-28
申请号：US14570685
申请日：2014-12-15
Applicant: AbbVie Inc.
Inventor： Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-Hsiang D. Chang , Thomas Seewoester
CPC classification number: C12N5/0037 , C07K16/241 , C07K16/244 , C07K16/2863 , C07K2317/14 , C07K2317/21 , C12N5/0043 , C12N2500/24 , C12N2500/32 , C12N2500/34 , C12N2500/38 , C12N2500/60 , C12N2500/74 , C12N2500/76 , C12N2501/105 , C12N2501/33
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Abstract translation: 本发明描述了用于在哺乳动物细胞培养物中产生重组蛋白例如抗体的改进的方法和组合物。 此外，本发明提供改进的细胞培养基，包括改良的生产培养基，饲料溶液和组合饲料，其可用于改善哺乳动物细胞培养物中的蛋白质生产力。
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公开(公告)号：US09073988B2
公开(公告)日：2015-07-07
申请号：US14563993
申请日：2014-12-08
Applicant: AbbVie Inc.
Inventor： Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-hsiang D. Chang , Thomas Seewoester
IPC: C12P1/00 , C12P21/04 , C12N5/07 , C12N5/16 , C12N5/10 , C12N5/00 , C12N5/02 , C07K16/24 , C07K16/00 , C07K16/28 , C12N5/073
CPC classification number: C12N5/0037 , C07K16/00 , C07K16/241 , C07K16/244 , C07K16/2869 , C07K2317/14 , C07K2317/21 , C12N5/0031 , C12N5/0603 , C12N2500/24 , C12N2500/25 , C12N2500/30 , C12N2500/32 , C12N2500/34 , C12N2500/38 , C12N2500/50 , C12N2500/60 , C12N2500/74 , C12N2500/76 , C12N2500/90 , C12N2501/10 , C12N2501/33 , C12N2510/02 , C12N2511/00
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Abstract translation: 本发明描述了用于在哺乳动物细胞培养物中产生重组蛋白例如抗体的改进的方法和组合物。 此外，本发明提供改进的细胞培养基，包括改良的生产培养基，饲料溶液和组合饲料，其可用于改善哺乳动物细胞培养物中的蛋白质生产力。
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公开(公告)号：US20140234905A1
公开(公告)日：2014-08-21
申请号：US14226579
申请日：2014-03-26
Applicant: AbbVie Inc.
Inventor： Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-Hsiang David Chang , Thomas Seewoester
CPC classification number: C12N5/0037 , C07K16/241 , C07K16/244 , C07K16/2863 , C07K2317/14 , C07K2317/21 , C12N5/0043 , C12N2500/24 , C12N2500/32 , C12N2500/34 , C12N2500/38 , C12N2500/60 , C12N2500/74 , C12N2500/76 , C12N2501/105 , C12N2501/33
Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
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