发明授权
- 专利标题： NAMPT and rock inhibitors
- 专利标题（中）： NAMPT和岩石抑制剂
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申请号： US13294303申请日： 2011-11-11
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公开(公告)号： US09302989B2公开(公告)日： 2016-04-05
- 发明人: Michael L. Curtin , Bryan K. Sorensen , Howard R. Heyman , Richard F. Clark , Kevin R. Woller , Omar J. Shah , Michael Michaelides , Chris Tse , Anil Vasudevan , Helmut Mack , Todd M. Hansen , Ramzi Sweis , Marina A. Pliushchev
- 申请人： Michael L. Curtin , Bryan K. Sorensen , Howard R. Heyman , Richard F. Clark , Kevin R. Woller , Omar J. Shah , Michael Michaelides , Chris Tse , Anil Vasudevan , Helmut Mack , Todd M. Hansen , Ramzi Sweis , Marina A. Pliushchev
- 申请人地址： US IL North Chicago
- 专利权人： AbbVie Inc.
- 当前专利权人： AbbVie Inc.
- 当前专利权人地址： US IL North Chicago
- 代理商 Glen J. Gesicki
- 主分类号： A01N43/38
- IPC分类号： A01N43/38 ; A61K31/40 ; C07D209/44 ; C07D401/12 ; C07D401/14 ; C07D403/10 ; C07D407/12 ; C07D407/14 ; C07D413/12 ; C07D417/12 ; C07D471/04 ; C07D491/048 ; C07D495/04 ; C07D403/12 ; C07D403/14 ; C07D405/12
摘要：
Disclosed are 1,3-dihydro-2H-isoindole compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of using the compounds to treat diseases during which NAMPT is expressed, e.g., cancer, metabolic disorders, and inflammatory disorders. Disclosed are 1,3-dihydro-2H-isoindole compounds which inhibit the activity of ROCK, compositions containing the compounds and methods of using the compounds to treat diseases during which ROCK is expressed, e.g., cancer, cardiovascular disorders, and inflammatory disorders.
公开/授权文献
- US20120122842A1 NAMPT AND ROCK INHIBITORS 公开/授权日：2012-05-17
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