Invention Grant
- Patent Title: Implantable swellable bio-resorbable polymer
- Patent Title (中): 可植入的可溶胀生物可吸收聚合物
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Application No.: US14003514Application Date: 2012-03-09
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Publication No.: US09320806B2Publication Date: 2016-04-26
- Inventor: Laurence Moine , Alexandre Laurent , Michel Wassef , Laurent Bedouet , Stephanie Louguet , Valentin Verret , Emeline Servais
- Applicant: Laurence Moine , Alexandre Laurent , Michel Wassef , Laurent Bedouet , Stephanie Louguet , Valentin Verret , Emeline Servais
- Applicant Address: FR Jouy en Josas FR Paris FR Paris FR Paris
- Assignee: Occlugel,Centre National De La Recherche Scientifique,Assistance Publique-Hopitaux De Paris,Universite Paris Diderot-Paris
- Current Assignee: Occlugel,Centre National De La Recherche Scientifique,Assistance Publique-Hopitaux De Paris,Universite Paris Diderot-Paris
- Current Assignee Address: FR Jouy en Josas FR Paris FR Paris FR Paris
- Agency: Banner & Witcoff, Ltd.
- Priority: EP11305254 20110309
- International Application: PCT/EP2012/054177 WO 20120309
- International Announcement: WO2012/120138 WO 20120913
- Main IPC: A61K47/48
- IPC: A61K47/48 ; A61K47/34 ; C08F220/18 ; C08F222/10 ; C08F224/00

Abstract:
The present invention relates to a polymer obtained from the polymerization of: (i) at least one monomer of formula (I) (CH2═CR1)CO—K (1) wherein: —K represents O—Z or N H—Z, Z representing (CR2R3)m-CH3, (CH2—CH2—O)m-H, (CH2—CH2—O)m-CH3, (CH2)m-NR4R5 with m representing an integer from 1 to 30; —R1, R2, R3, R4 and R5 independently represent H or a C1-C6 alkyl; (ii) at least between 0.1 and 50% mol, advantageously between 1 and 30% mol, more advantageously between 1 and 20 mol % of a cyclic monomer having a exomethylene group of formula (II) wherein: — R6, R7, R8 and R9 represent independently H or a C5-C7 aryl group or R6 and R9 are absent and R7 and R8 form together with the carbon atom on which they are bonded a C5-C7 aryl group; —i and j represent independently an integer chosen between 0 and 2; —X represents either O or X is not present and in this latter case, CR6R7 and CR8R9 are linked via a single bond C—C and (iii) at least one bio-resorbable block copolymer cross-linker.
Public/Granted literature
- US20130344159A1 IMPLANTABLE SWELLABLE BIO-RESORBABLE POLYMER Public/Granted day:2013-12-26
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