Invention Grant
- Patent Title: Methods for preparing anti-viral nucleotide analogs
-
Application No.: US14681955Application Date: 2015-04-08
-
Publication No.: US09346841B2Publication Date: 2016-05-24
- Inventor: Denise A. Colby , Andrew Anthony Martins , Benjamin James Roberts , Robert William Scott , Nicole S. White
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Agency: Morrison & Foerster LLP
- Main IPC: C07F9/6512
- IPC: C07F9/6512 ; C07F9/6561 ; C07F9/6558
Abstract:
Methods for isolating 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
Public/Granted literature
- US20150291638A1 METHODS FOR PREPARING ANTI-VIRAL NUCLEOTIDE ANALOGS Public/Granted day:2015-10-15
Information query
