Invention Grant
US09353168B2 Method of reducing cell death by administering a paracrine factor derived from a mesenchymal stem cell
有权
通过施用源自间充质干细胞的旁分泌因子来减少细胞死亡的方法
- Patent Title: Method of reducing cell death by administering a paracrine factor derived from a mesenchymal stem cell
- Patent Title (中): 通过施用源自间充质干细胞的旁分泌因子来减少细胞死亡的方法
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Application No.: US14256174Application Date: 2014-04-18
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Publication No.: US09353168B2Publication Date: 2016-05-31
- Inventor: Victor J. Dzau , Maria Mirotsou
- Applicant: The Brigham and Women's Hospital, Inc. , Duke University
- Applicant Address: US MA Boston US NC Durham
- Assignee: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.,DUKE UNIVERSITY
- Current Assignee: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.,DUKE UNIVERSITY
- Current Assignee Address: US MA Boston US NC Durham
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: A61K38/17
- IPC: A61K38/17 ; C07K14/435 ; C07K14/475 ; A61K38/18 ; C12N15/09 ; C12N15/63 ; C12N5/10
Abstract:
A purified paracrine factor of a mesenchymal stem cell, such as a Secreted frizzled related protein (Sfrp) is useful to reduce cell death and/or tissue injury associated with ischemic conditions.
Public/Granted literature
- US20140296152A1 Stem Cell Derived Factors for Treating Pathologic Conditions Public/Granted day:2014-10-02
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