发明授权
- 专利标题: Method for glycosylation of flavonoid compounds
- 专利标题(中): 黄酮类化合物糖基化方法
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申请号: US12523065申请日: 2008-01-18
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公开(公告)号: US09364492B2公开(公告)日: 2016-06-14
- 发明人: Misa Ochiai , Harukazu Fukami , Masahiro Nakao , Akio Noguchi
- 申请人: Misa Ochiai , Harukazu Fukami , Masahiro Nakao , Akio Noguchi
- 申请人地址: JP Osaka
- 专利权人: SUNTORY HOLDINGS LIMITED
- 当前专利权人: SUNTORY HOLDINGS LIMITED
- 当前专利权人地址: JP Osaka
- 代理机构: Greenblum & Bernstein, P.L.C.
- 优先权: JP2007-010766 20070119
- 国际申请: PCT/JP2008/050619 WO 20080118
- 国际公布: WO2008/088047 WO 20080724
- 主分类号: C07H15/203
- IPC分类号: C07H15/203 ; C07H17/065 ; A23L2/52 ; A61K31/7048 ; A23L1/03 ; A23L1/30 ; A61K8/60 ; A61K31/7034 ; A61Q19/00 ; C12P19/14
摘要:
The present invention provides a method for preparing a glycoside of a flavonoid compound, which comprises the step of treating flavonoid and a glycosyl donor with an enzymatic agent having glycosylation activity and being derived from the genus Trichoderma (preferably Trichoderma viride or Trichoderma reesei). Such a flavonoid compound includes a catechin compound or a methylated derivative thereof, and the glycosyl donor includes a carbohydrate containing a maltotriose residue (preferably maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose, dextrin, γ-cyclodextrin or soluble starch). Glycosides obtained by the present invention have higher water solubility, improved taste, and increased stability. The present invention also provides novel glycosides of catechin compounds, which are obtained by the method of the present invention.
公开/授权文献
- US20100256345A1 METHOD FOR GLYCOSYLATION OF FLAVONOID COMPOUNDS 公开/授权日:2010-10-07
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