Invention Grant
US09452564B2 Multi-scale wrinkles for functional alignment of stem cells and cardiac derivatives
有权
用于干细胞和心脏衍生物功能匹配的多尺度皱纹
- Patent Title: Multi-scale wrinkles for functional alignment of stem cells and cardiac derivatives
- Patent Title (中): 用于干细胞和心脏衍生物功能匹配的多尺度皱纹
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Application No.: US13654275Application Date: 2012-10-17
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Publication No.: US09452564B2Publication Date: 2016-09-27
- Inventor: Michelle Khine , Ronald A. Li , Cheng-Wei Chen
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Foley & Lardner LLP
- Agent Antionette F. Konski; Lydia B. Choi
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/071 ; B29C59/14 ; B29C61/02

Abstract:
Provided are methods of preparing a biocompatible textured surface on a thermoplastic material comprising treating the material with a plasma and subsequently shrinking the substrate to induce formation of textures. The textured surfaces are useful in one aspect, to align cells such as stem cells.
Public/Granted literature
- US20130040335A1 MULTI-SCALE WRINKLES FOR FUNCTIONAL ALIGNMENT OF STEM CELLS AND CARDIAC DERIVATIVES Public/Granted day:2013-02-14
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