A memory structure comprises a semiconductor strip having a multi-gate channel region, the p-type terminal region adjacent a first side of the channel region and an n-type terminal region adjacent the second side of the channel region. A plurality of word lines is arranged to cross the semiconductor strip at cross points in the channel region. The bit line is coupled to a first end of the semiconductor strip, and a reference line is coupled to a second end of the semiconductor strip. Charge storage structures are disposed between the word lines in the plurality word lines and the channel region of the semiconductor strip, whereby memory cells are disposed in series along the semiconductor strip between the bit line and the reference line. Biasing unselected word lines can be used to select n-channel or p-channel modes in a single selected cell for read, program or erase.