发明授权
- 专利标题： Synthetic glucopyranosyl lipid adjuvants
- 专利标题（中）： 合成的吡喃葡萄糖基脂质佐剂
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申请号： US14222481申请日： 2014-03-21
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公开(公告)号： US09480740B2公开(公告)日： 2016-11-01
- 发明人: Steven G. Reed , Darrick Carter
- 申请人： Infectious Disease Research Institute
- 申请人地址： US WA Seattle
- 专利权人： INFECTIOUS DISEASE RESEARCH INSTITUTE
- 当前专利权人： INFECTIOUS DISEASE RESEARCH INSTITUTE
- 当前专利权人地址： US WA Seattle
- 代理机构： Morrison & Foerster LLP
- 主分类号： A61K39/39
- IPC分类号： A61K39/39 ; A61K39/00 ; A61K39/04 ; C07H15/12 ; A61K39/21 ; A61K39/235 ; A61K39/245 ; A61K39/275 ; C07H15/20
摘要：
Compounds, particularly, glucopyranosyl lipid adjuvant (GLA) compounds, having the following structure (I) are provided: or a pharmaceutically acceptable salt thereof, wherein L1, L2, L3, L4, L5, L6, L7, L8, L9, L10, Y1, Y2, Y3, Y4, R1, R2, R3, R4, R5, R6, are as defined herein. Pharmaceutical compositions, vaccine compositions, and related methods for inducing or enhancing immune responses, are also provided.
公开/授权文献
- US20140322268A1 SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS 公开/授权日：2014-10-30
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