Invention Grant
- Patent Title: Fluorescent probe for high-sensitivity pancreatic fluid detection, and method for detecting pancreatic fluid
- Patent Title (中): 用于高灵敏度胰液检测的荧光探针,以及胰液检测方法
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Application No.: US14398202Application Date: 2013-05-29
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Publication No.: US09506102B2Publication Date: 2016-11-29
- Inventor: Yasuteru Urano , Masayo Sakabe , Tetsuo Nagano , Takeaki Ishizawa , Suguru Yamashita , Norihiro Kokudo , Mako Kamiya
- Applicant: THE UNIVERSITY OF TOKYO
- Applicant Address: JP Tokyo
- Assignee: THE UNIVERSITY OF TOKYO
- Current Assignee: THE UNIVERSITY OF TOKYO
- Current Assignee Address: JP Tokyo
- Agency: Greenblum and Bernstein, P.L.C.
- Priority: JP2012-123478 20120530
- International Application: PCT/JP2013/064921 WO 20130529
- International Announcement: WO2013/180181 WO 20131205
- Main IPC: C12Q1/37
- IPC: C12Q1/37 ; C12Q1/48 ; C09B11/24 ; C07D493/10 ; C09K11/06

Abstract:
A fluorescent probe for detecting pancreatic fluid containing a compound or salt thereof represented by formula (I) below. (In the formula, A represents an amino acid residue or N-substituted amino acid residue, with A forming an amide bond with the adjacent NH in the formula; R1 represents a hydrogen atom or 1 to 4 same or different substituent groups that bond with a benzene ring; R2, R3, R4, R5, R6, and R7 each independently represent a hydrogen atom, a hydroxyl group, an alkyl group, or a halogen atom; R8 and R9 each independently represent a hydrogen atom or an alkyl group; and X represents a C1-C3 alkylene group).
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