Invention Grant
US09532987B2 Use of a combination of a MEK inhibitor and an ERK inhibitor for treatment of hyperproliferative diseases
有权
使用MEK抑制剂和ERK抑制剂的组合来治疗过度增殖性疾病
- Patent Title: Use of a combination of a MEK inhibitor and an ERK inhibitor for treatment of hyperproliferative diseases
- Patent Title (中): 使用MEK抑制剂和ERK抑制剂的组合来治疗过度增殖性疾病
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Application No.: US14473311Application Date: 2014-08-29
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Publication No.: US09532987B2Publication Date: 2017-01-03
- Inventor: Marcia Belvin , John Moffat , Mark Merchant
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/397 ; A61K31/435 ; A61K31/437 ; A61K31/5025
Abstract:
The invention provides combinations comprising a MEK inhibitor (such as GDC-0973 or GDC-0623), or a pharmaceutically acceptable salt thereof and an ERK inhibitor (such as GDC-0994). The combinations are particularly useful for treating hyperproliferative disorders, such as cancer.
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