Invention Grant
US09533958B2 Process or the preparation of 4-amino 1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-Enyl)-1H-pyrimidin-2-one
有权
4-氨基1 - （（1S，4R，5S）-2-氟-4,5-二羟基-3-羟甲基 - 环戊-2-烯基）-1H-嘧啶-2-酮的方法或制备
- Patent Title: Process or the preparation of 4-amino 1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-Enyl)-1H-pyrimidin-2-one
- Patent Title (中): 4-氨基1 - （（1S，4R，5S）-2-氟-4,5-二羟基-3-羟甲基 - 环戊-2-烯基）-1H-嘧啶-2-酮的方法或制备
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Application No.: US14845968Application Date: 2015-09-04
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Publication No.: US09533958B2Publication Date: 2017-01-03
- Inventor: Haifeng Yin , Deog Joong Kim , Eliezer Falb , Leigh Andre Pearcey , Jonathan Cummins , Petra Dieterich , Jean-Francois Carniaux , Yi Wang , Vikram Chandrakant Purohit
- Applicant: Rexahn Pharmaceuticals, Inc.
- Applicant Address: US MD Rockville
- Assignee: Rexahn Pharmaceuticals, Inc.
- Current Assignee: Rexahn Pharmaceuticals, Inc.
- Current Assignee Address: US MD Rockville
- Agency: Venable LLP
- Agent Keith G. Haddaway; Annette K. Kwok
- Main IPC: C07D239/47
- IPC: C07D239/47 ; C07F7/18 ; C07D317/44 ; C07D405/04
Abstract:
Processes for the preparation of 4-amino-1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one (13, RX-3117) and its intermediates are described.
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